{"id":"W4386024076","doi":"10.1097/01.hs9.0000967492.06443.0a","title":"S145: VENETOCLAX-OBINUTUZUMAB FOR PREVIOUSLY UNTREATED CHRONIC LYMPHOCYTIC LEUKEMIA: 6-YEAR RESULTS OF THE RANDOMIZED CLL14 STUDY","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Obinutuzumab; Venetoclax; Medicine; Chronic lymphocytic leukemia; Internal medicine; Tolerability; Chlorambucil; Bendamustine; Oncology; Hazard ratio; Interquartile range; Clinical endpoint; Leukemia; Gastroenterology; Randomized controlled trial; Cyclophosphamide; Chemotherapy; Adverse effect; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001987775,0.0003913489,0.00140271,0.0001257368,0.0001933038,0.00003347228,0.0005338259,0.0002636437,0.0002069162],"category_scores_gemma":[0.002550913,0.0002526398,0.0006329545,0.001396195,0.0004067057,0.00006980717,0.0003265354,0.0003130006,0.0002633126],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.1219166,"about_ca_system_score_gemma":0.06929772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002957791,"about_ca_topic_score_gemma":0.0004925134,"domain_scores_codex":[0.9957978,0.0004002736,0.001110714,0.0007297988,0.001021782,0.0009396693],"domain_scores_gemma":[0.9957898,0.001632696,0.000348108,0.001630423,0.0003738547,0.0002251576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.719355,0.0005819807,0.0006285938,0.009697509,0.006417632,0.001041519,0.01399687,0.04472646,0.006185211,0.0016859,0.186848,0.008835256],"study_design_scores_gemma":[0.8672258,0.001418253,0.0002145408,0.000875882,0.0008360375,0.0001055684,0.001410083,0.1162544,0.007399514,0.0002336212,0.003715014,0.0003113067],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825615,0.001127546,0.00002990358,0.0001612687,0.0003503516,0.01111372,0.00006186173,0.0003425977,0.004251297],"genre_scores_gemma":[0.9763194,0.0002430284,0.0001213835,0.00005707806,0.0003413322,0.0009795687,0.00008529203,0.0001158911,0.02173704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.183133,"threshold_uncertainty_score":0.9999926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02367475763571688,"score_gpt":0.3104929278816977,"score_spread":0.2868181702459809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}