{"id":"W4386024586","doi":"10.1097/01.hs9.0000968552.93087.6b","title":"P411: LONGITUDINAL CHARACTERIZATION OF MOLECULAR VARIANTS AT REMISSION AND RELAPSE: SUBANALYSIS OF THE QUAZAR AML-001 TRIAL","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Internal medicine; Medicine; NPM1; Oncology; Myeloid leukemia; Azacitidine; Cytogenetics; Gastroenterology; Randomization; Bone marrow; Myeloid; Clinical trial; Gene; Biology; Genetics; DNA methylation; Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004260417,0.000118695,0.000370152,0.00008035438,0.00007086775,0.000006525994,0.0001249138,0.0001376111,0.000514319],"category_scores_gemma":[0.000416465,0.00008160839,0.000117924,0.0009054294,0.0001052084,0.00005359867,0.0002032342,0.0001703255,0.00002238884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001083556,"about_ca_system_score_gemma":0.0001553646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006909919,"about_ca_topic_score_gemma":0.000009145641,"domain_scores_codex":[0.9985012,0.0001185759,0.0003745991,0.0002604444,0.0005419897,0.0002031279],"domain_scores_gemma":[0.9989592,0.00007924061,0.0002053321,0.0004964401,0.0001620277,0.00009780275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004611675,0.0001001218,0.01679528,0.0002860014,0.0001708727,0.00006045316,0.0001720985,0.000005993709,0.9743371,0.0001205344,0.001340931,0.001998953],"study_design_scores_gemma":[0.04713557,0.0007791506,0.4031593,0.000684996,0.0008710832,0.00009776282,0.0002500043,0.00617316,0.5376909,0.0001465327,0.002695565,0.0003159391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975046,0.00009857132,0.00007668629,0.001028868,0.00007389185,0.0004723723,0.00001766987,0.00002700943,0.0007003153],"genre_scores_gemma":[0.9927248,0.0001909981,0.0001134406,0.00003301946,0.00007333199,0.00001351669,0.0001088372,0.00002592874,0.006716079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4366462,"threshold_uncertainty_score":0.5631433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02367151887753247,"score_gpt":0.2916650467869095,"score_spread":0.267993527909377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}