{"id":"W4386033551","doi":"10.1038/s42255-023-00885-w","title":"Mitochondrial function and phenotype are defined by bioenergetics","year":2023,"lang":"en","type":"letter","venue":"Nature Metabolism","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; McGill University","funders":"","keywords":"Bioenergetics; Phenotype; Function (biology); Energy metabolism; Mitochondrion; Biology; Chemistry; Genetics; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002216944,0.0006507635,0.001091509,0.0005068927,0.001479196,0.002657373,0.0009059229,0.01723521,0.003470526],"category_scores_gemma":[0.01017428,0.0003614965,0.0005926425,0.0003695143,0.003890047,0.002207576,0.001122947,0.02100972,0.002424539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002700838,"about_ca_system_score_gemma":0.0009905536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001061755,"about_ca_topic_score_gemma":0.00219358,"domain_scores_codex":[0.9987457,0.0003790552,0.0001436347,0.000166345,0.000412145,0.0001531691],"domain_scores_gemma":[0.9960263,0.002491891,0.0002501809,0.0002305631,0.0005145455,0.000486552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007581558,0.0001217186,0.002238897,0.0001492919,0.00005174675,0.008309637,0.0001847444,0.0001998213,0.003755598,0.02785081,0.9059849,0.05039475],"study_design_scores_gemma":[0.0005177433,0.0002081713,0.005450816,0.0002702367,0.00006069801,0.008680832,0.0003682426,0.001579951,0.003120568,0.1266281,0.8530017,0.0001128611],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001556758,0.003880742,0.0005962399,0.9577753,0.03149131,0.00001320717,0.00003725668,0.00004214703,0.004607048],"genre_scores_gemma":[0.03681107,0.006588506,0.00109575,0.7675569,0.1692771,0.0001039362,0.00004749978,0.00006241394,0.0184568],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01723521,"threshold_uncertainty_score":0.01959604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007665889765237167,"score_gpt":0.2262777011294287,"score_spread":0.2186118113641916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}