{"id":"W4386034430","doi":"10.1016/j.scitotenv.2023.166443","title":"Exercise training inhibits macrophage-derived IL-17A-CXCL5-CXCR2 inflammatory axis to attenuate pulmonary fibrosis in mice exposed to silica","year":2023,"lang":"en","type":"article","venue":"The Science of The Total Environment","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"CXCL5; Silicosis; Chemokine; CXC chemokine receptors; Scavenger receptor; Medicine; Fibrosis; Immunology; Inflammation; TLR4; Receptor; Pulmonary fibrosis; Chemistry; Internal medicine; Chemokine receptor; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002009277,0.0006572,0.0005558194,0.0003302125,0.0002424461,0.000286587,0.0003034079,0.0005179131,0.003383439],"category_scores_gemma":[0.0001478007,0.0002813009,0.0005711564,0.0001097871,0.0005863469,0.0002893326,0.0002914831,0.001644327,0.000362365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059803,"about_ca_system_score_gemma":0.0004504403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001233422,"about_ca_topic_score_gemma":0.002862929,"domain_scores_codex":[0.9997525,0.0000303075,0.00001945516,0.00005000952,0.00003603415,0.0001117965],"domain_scores_gemma":[0.9998857,0.000006562223,0.0000271556,0.000009990366,0.00001229966,0.00005832653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01201398,0.003661852,0.002441735,0.0003574462,0.00009793186,0.0001304126,0.0001282172,0.0003397958,0.9687359,0.000192006,0.0005901169,0.01131056],"study_design_scores_gemma":[0.002504495,0.0343289,0.1113189,0.000249228,0.0008796056,0.0004526993,0.001035859,0.007977518,0.8307313,0.0008829515,0.009546095,0.00009247664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995141,0.001304381,0.001522834,0.0003762914,0.0002219053,0.00005083535,0.0002863395,0.0001328248,0.000963352],"genre_scores_gemma":[0.9914142,0.000969231,0.0008742805,0.0002393316,0.00006023889,0.0001845468,0.0003609342,0.00002430248,0.005872876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003383439,"threshold_uncertainty_score":0.01131868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718688524994847,"score_gpt":0.2331481319006322,"score_spread":0.2159612466506838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}