{"id":"W4386046159","doi":"10.1002/ijc.34686","title":"Validation of novel <scp>DNA</scp> methylation markers in cervical precancer and cancer","year":2023,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Cervical intraepithelial neoplasia; Cervical cancer; Medicine; Receiver operating characteristic; Cancer; DNA methylation; Methylation; Oncology; Internal medicine; Area under curve; Gene; Biology; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002368038,0.0004301524,0.0004693692,0.0008329096,0.0004004328,0.0005574641,0.0004682187,0.0004281174,0.0006463117],"category_scores_gemma":[0.003248384,0.0002146754,0.0003307308,0.0005435225,0.000464609,0.0002047633,0.0005178509,0.0004305752,0.0002633573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003624162,"about_ca_system_score_gemma":0.0006343207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003415962,"about_ca_topic_score_gemma":0.005326604,"domain_scores_codex":[0.9990169,0.0002766392,0.00007500536,0.0003089167,0.0002586512,0.0000638173],"domain_scores_gemma":[0.9984774,0.0005550114,0.0002802489,0.000193243,0.0003583437,0.0001357858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001517708,0.00021745,0.7386048,0.0002106985,0.0003576729,0.0002664058,0.0003872351,0.004642487,0.222902,0.0001801206,0.0004323161,0.03028102],"study_design_scores_gemma":[0.00007456722,0.001224002,0.8543103,0.00002801703,0.0002622399,0.001042327,0.0001256503,0.01548986,0.1244586,0.0002294351,0.002726714,0.00002818877],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943777,0.000632267,0.003512518,0.00006522879,0.00001082687,0.00005371205,0.0008314616,0.00005093426,0.0004653652],"genre_scores_gemma":[0.9930834,0.0001647887,0.004603789,0.00005103021,0.00001281093,0.00006527044,0.001632781,0.00001346527,0.0003726327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003415962,"threshold_uncertainty_score":0.01252353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05016803508464705,"score_gpt":0.4076402107230303,"score_spread":0.3574721756383832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}