{"id":"W4386046570","doi":"10.1007/s40268-023-00428-4","title":"Tremor Induced by Cyclosporine, Tacrolimus, Sirolimus, or Everolimus: A Review of the Literature","year":2023,"lang":"en","type":"review","venue":"Drugs in R&D","topic":"Oral and gingival health research","field":"Health Professions","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Tacrolimus; Everolimus; Sirolimus; Medicine; Calcineurin; Dosing; Therapeutic drug monitoring; Adverse effect; Pharmacology; Internal medicine; Ciclosporin; Transplantation; Drug","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003520955,0.0007321511,0.003572107,0.0004257224,0.0004274205,0.00001505573,0.001612868,0.001209248,0.0004818533],"category_scores_gemma":[0.001454267,0.000379076,0.000741559,0.005050178,0.00009779715,0.0001120674,0.0009096834,0.005348978,0.000751945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005571589,"about_ca_system_score_gemma":0.00300232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004458979,"about_ca_topic_score_gemma":0.0001068351,"domain_scores_codex":[0.9904157,0.003320196,0.002878601,0.0008236174,0.001073279,0.001488594],"domain_scores_gemma":[0.9940175,0.002458355,0.00137107,0.001532878,0.0003015132,0.0003186802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003440311,0.00007752683,0.00003708542,0.6956304,0.00004629412,0.00001831153,0.0007707487,1.615063e-8,1.658348e-7,0.00006919121,0.06522775,0.2380882],"study_design_scores_gemma":[0.0002654489,0.00003924212,0.00004302577,0.4102716,0.00009085128,0.000003117984,0.00009104225,8.460192e-7,1.207769e-7,0.0000600172,0.5889235,0.0002111771],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001064464,0.9870061,6.05702e-8,0.001918061,0.001452688,0.006545556,0.0009826975,0.0001128145,0.001875572],"genre_scores_gemma":[0.00001002588,0.9723024,0.00001563255,0.001942976,0.0006770817,0.001325417,0.0003123375,0.0001790893,0.02323505],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5236957,"threshold_uncertainty_score":0.9998661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2153648129055369,"score_gpt":0.5519977062624285,"score_spread":0.3366328933568916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}