{"id":"W4386055832","doi":"10.1021/acsinfecdis.3c00113","title":"Potent Antifungal Activity of Penta-<i>O</i>-galloyl-β-<scp>d</scp>-Glucose against Drug-Resistant <i>Candida albicans</i>, <i>Candida auris</i>, and Other Non-<i>albicans Candida</i> Species","year":2023,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University; University of Toronto","funders":"National Center for Complementary and Integrative Health; Canadian Institutes of Health Research; National Institutes of Health; Canadian Institute for Advanced Research","keywords":"Candida albicans; Candida auris; Microbiology; Corpus albicans; Biology; Antifungal drug; Cytotoxicity; Multiple drug resistance; Minimum inhibitory concentration; Drug resistance; In vitro; Antimicrobial; Antifungal; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005872305,0.0002838327,0.0001096649,0.0001845518,0.00005489378,0.0001306771,0.0001340826,0.0001299698,0.001348158],"category_scores_gemma":[0.00005193226,0.00006050761,0.0001399443,0.0001255552,0.00009542666,0.00009819992,0.0001045454,0.0001980246,0.0001931848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007069608,"about_ca_system_score_gemma":0.0001028017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006281156,"about_ca_topic_score_gemma":0.0006299564,"domain_scores_codex":[0.9999565,0.00000829891,0.000005265539,0.000007125347,0.00001294523,0.000009796016],"domain_scores_gemma":[0.9999689,0.000007335835,0.000008231673,0.000002991183,0.000005397038,0.000007220836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001028409,0.000014593,0.00009055914,0.00004329089,0.000002414194,0.00005293937,0.000007100517,0.00004212841,0.9981648,0.00001607646,0.00003715561,0.001426189],"study_design_scores_gemma":[0.000007640991,0.0003964635,0.003261931,0.000006455516,0.00001118216,0.0001723157,0.00001470709,0.0002312088,0.994783,0.00001013791,0.001102438,0.000002647666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920061,0.003132491,0.001240276,0.0001023544,0.00002687683,0.0000223108,0.0005865376,0.00007918131,0.002803848],"genre_scores_gemma":[0.9931791,0.001781272,0.001928757,0.00004722202,0.000008833722,0.00001245288,0.0008411968,0.00001432421,0.002186749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001348158,"threshold_uncertainty_score":0.004510045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051548115868922,"score_gpt":0.2499230348516339,"score_spread":0.2394075536929446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}