{"id":"W4386069245","doi":"10.1111/sji.13325","title":"Relapsing/remitting multiple sclerosis: A speculative model and its implications for a novel treatment","year":2023,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Multiple sclerosis; Immune system; Antigen; Immunology; Subclass; Inflammatory response; Inflammation; Medicine; Biology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003575741,0.0002925645,0.0006380312,0.0004630584,0.0005012229,0.00002201825,0.0003003044,0.0003713799,0.00002904293],"category_scores_gemma":[0.000262303,0.0002429921,0.0002535967,0.0003097345,0.0003203432,0.0001643951,0.0001110906,0.0003622973,0.00006396066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693701,"about_ca_system_score_gemma":0.0001469348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001852088,"about_ca_topic_score_gemma":0.00001203919,"domain_scores_codex":[0.9981743,0.0001162744,0.0007200357,0.00033655,0.00002893426,0.0006239496],"domain_scores_gemma":[0.9983206,0.0004862846,0.0006018091,0.0002552979,0.0002902409,0.00004577425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005532874,0.0002111921,0.001526094,0.00001130111,0.000763734,0.000003216994,0.001251802,0.0001763451,0.985823,0.002579289,0.0003769696,0.006723797],"study_design_scores_gemma":[0.06341109,0.01173316,0.1023031,0.001361382,0.001526635,0.006802388,0.006834091,0.003052006,0.7720138,0.01438652,0.01455705,0.002018743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825953,0.01199328,0.002049271,0.001688477,0.0008723458,0.000449758,0.0001497975,0.0000737946,0.000127926],"genre_scores_gemma":[0.9949772,0.001905516,0.0008153056,0.00005897554,0.0000573647,0.00006309417,0.00006279002,0.00003793848,0.002021763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2138091,"threshold_uncertainty_score":0.9908932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07055649834545409,"score_gpt":0.2761107740538428,"score_spread":0.2055542757083887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}