{"id":"W4386092153","doi":"10.1016/j.vaccine.2023.08.036","title":"Development and characterization of a plant-derived norovirus-like particle vaccine","year":2023,"lang":"en","type":"article","venue":"Vaccine","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Medicago (Canada); McGill University Health Centre","funders":"","keywords":"Immunogenicity; Virology; Nicotiana benthamiana; Biology; Virus-like particle; Immune system; Titer; Antibody; Antigen; Virus; Antibody titer; Microbiology; Recombinant DNA; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005205879,0.00006270354,0.00007760715,0.00002055575,0.00003962686,0.000004929676,0.0000511894,0.00003685689,0.00001366569],"category_scores_gemma":[0.000003888338,0.00005582778,0.00001302617,0.00009486813,0.000002528503,0.000002370715,0.00003405732,0.00001869217,0.00001211285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001816895,"about_ca_system_score_gemma":0.00001836178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003438153,"about_ca_topic_score_gemma":0.00003937241,"domain_scores_codex":[0.9995672,0.000006543892,0.0001401953,0.0001398772,0.0000410796,0.0001051252],"domain_scores_gemma":[0.9997875,0.000003946586,0.00003887243,0.000113296,0.00001750519,0.00003885882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004449911,0.00002110168,0.004173453,0.00001147305,0.00002002429,6.30117e-7,0.0000701226,0.00000157054,0.9920972,0.00003379132,0.0002707691,0.003255396],"study_design_scores_gemma":[0.0004796876,0.000030278,0.2444344,0.000005322446,0.000007183349,0.000003960793,0.00001745898,0.00007759024,0.6957062,0.000003077452,0.0591694,0.00006538729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991807,0.00004011502,0.0003326699,0.000189713,0.00002544093,0.000103765,0.00009268102,0.00001902158,0.00001591038],"genre_scores_gemma":[0.9982928,0.0002550806,0.000214821,0.00007966039,0.00003505664,0.00002294042,0.0008802702,0.000008222604,0.0002111403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2963909,"threshold_uncertainty_score":0.2276591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0132419055000677,"score_gpt":0.2268053418705698,"score_spread":0.2135634363705021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}