{"id":"W4386102821","doi":"10.1016/j.clim.2023.109746","title":"Mitochondrial-mediated inflammation and platelet activation in giant cell arteritis","year":2023,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; McMaster University","funders":"National Center for Research Resources; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Eye Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Platelet activation; Inflammation; Platelet; Mitochondrion; Cytokine; Peripheral blood mononuclear cell; Immunology; Opsonin; Extracellular; Biology; Medicine; Phagocytosis; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002267779,0.0001915317,0.0002132758,0.0003502903,0.0001444523,0.0003133896,0.0001031662,0.0004467219,0.001082602],"category_scores_gemma":[0.0004930567,0.0001325638,0.0001500665,0.0002882734,0.0002163781,0.0002004635,0.0002238678,0.000402072,0.0001363502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001557132,"about_ca_system_score_gemma":0.00009255731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003276436,"about_ca_topic_score_gemma":0.0003638021,"domain_scores_codex":[0.9998561,0.00006561662,0.00001148421,0.00001992934,0.00002658045,0.00002033276],"domain_scores_gemma":[0.9997723,0.00005125603,0.0001052842,0.00001020689,0.00001706967,0.00004401324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01234337,0.0005189267,0.6448814,0.0006704866,0.0003537193,0.009114266,0.0009887641,0.0004478366,0.2921612,0.0006251229,0.0008154579,0.03707941],"study_design_scores_gemma":[0.00009571353,0.001244442,0.9781061,0.00005241219,0.0001025837,0.009509951,0.0003889472,0.0006708354,0.008153857,0.000583784,0.001079963,0.00001138565],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952924,0.004004482,0.0001614394,0.00008452141,0.000009963221,0.000006223792,0.0000350956,0.000006009579,0.0003999828],"genre_scores_gemma":[0.9991564,0.0005509278,0.0001226553,0.00001997916,0.00001363838,0.000004024323,0.00003012045,6.268423e-7,0.0001015731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001082602,"threshold_uncertainty_score":0.003621638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02439425070525855,"score_gpt":0.3086597291493086,"score_spread":0.28426547844405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}