{"id":"W4386112861","doi":"10.2139/ssrn.4450374","title":"Cell Characterization, Graft Evaluation, and Yield of Islet-Like Cells Differentiated From Patient-Derived iPSCs","year":2023,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Islet; Induced pluripotent stem cell; Yield (engineering); Characterization (materials science); Cell biology; Cell; Computational biology; Chemistry; Biology; Diabetes mellitus; Nanotechnology; Endocrinology; Biochemistry; Materials science; Embryonic stem cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006720363,0.0003637412,0.0004505597,0.0004983919,0.0002320549,0.0009355739,0.0002399409,0.0004732972,0.002354662],"category_scores_gemma":[0.0006206994,0.0001367751,0.0003361629,0.000384239,0.0002309846,0.0002564056,0.0003913848,0.0008687042,0.001159547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001221667,"about_ca_system_score_gemma":0.0001259285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001611598,"about_ca_topic_score_gemma":0.0001302506,"domain_scores_codex":[0.99967,0.00003651258,0.00006193745,0.00007170338,0.0001182685,0.00004157844],"domain_scores_gemma":[0.9997005,0.00008655152,0.00002555376,0.00006242532,0.00008278564,0.00004213468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002619294,0.0000958239,0.002767119,0.00007392597,0.00002187172,0.0002383566,0.000233785,0.0002540787,0.9904047,0.0002803408,0.0001215377,0.005246493],"study_design_scores_gemma":[0.00001235648,0.0002261754,0.006506349,0.00001834501,0.0001053841,0.0005612537,0.00009055869,0.001119229,0.9872162,0.0001640102,0.003970735,0.000009415657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782335,0.001042224,0.01504643,0.00007485982,0.00004630101,0.0001746048,0.00159913,0.000195831,0.003587124],"genre_scores_gemma":[0.9780077,0.001340766,0.01078654,0.0001205648,0.00002263759,0.0002233597,0.005437149,0.0002305621,0.003830672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002354662,"threshold_uncertainty_score":0.007877111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02014410582682085,"score_gpt":0.2424622674752194,"score_spread":0.2223181616483986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}