{"id":"W4386116998","doi":"10.1002/phar.2842","title":"International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists","year":2023,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"British Society for Antimicrobial Chemotherapy","keywords":"Medicine; Guideline; Dosing; Intensive care medicine; Pharmacy; Antibiotics; Clinical pharmacy; Therapeutic drug monitoring; Antimicrobial chemotherapy; Pharmacology; Pharmacokinetics; Family medicine; Pathology; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.002040297,0.0004243351,0.001650794,0.00008488556,0.0005042679,0.00001953502,0.0003877553,0.0001226513,0.00008967174],"category_scores_gemma":[0.0001360125,0.0002945749,0.001792719,0.0004301251,0.007190125,0.0001316477,0.0001483435,0.0006192446,9.397574e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004071831,"about_ca_system_score_gemma":0.0003121705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009184238,"about_ca_topic_score_gemma":0.000002132807,"domain_scores_codex":[0.9954136,0.0009833848,0.002463266,0.0004307244,0.0003197977,0.0003892339],"domain_scores_gemma":[0.9870352,0.007814747,0.00313269,0.0002401809,0.00155822,0.0002190141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.005096037,0.0029168,0.09772532,0.001669755,0.007954822,0.000001356695,0.004883235,0.0001187544,0.5370453,0.00001287264,0.3102229,0.03235288],"study_design_scores_gemma":[0.286766,0.02119696,0.1248428,0.001954063,0.03504965,0.0009936591,0.01456005,0.08673602,0.2253782,0.0005653689,0.1994455,0.002511774],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978224,0.004356169,0.001524904,0.009174103,0.0007757644,0.001818732,0.004087646,0.00003443478,0.000004256105],"genre_scores_gemma":[0.8535644,0.140893,0.0008964068,0.003774699,0.0006165864,0.000009094222,0.0001569537,0.00006818347,0.00002061396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3116671,"threshold_uncertainty_score":0.9999506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0528747821795888,"score_gpt":0.4097860310646249,"score_spread":0.3569112488850361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}