{"id":"W4386122247","doi":"10.3389/fcimb.2023.1205829","title":"Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking","year":2023,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Medical Research Council; South African Medical Research Council; National Research Foundation; Innovation Saskatchewan; Howard Hughes Medical Institute; National Science Foundation","keywords":"Peptidoglycan; Cell wall; Mycobacterium smegmatis; Biochemistry; Bacterial cell structure; Biology; Cell biology; Fluorescence microscope; Bacteria; Chemistry; Fluorescence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230305,0.0003222423,0.0001863364,0.0001101023,0.0001649045,0.0002727981,0.0001359986,0.0003386301,0.0008883076],"category_scores_gemma":[0.0001678917,0.0001390215,0.0002608066,0.0001309756,0.0002039146,0.0001882311,0.0002685341,0.0003416768,0.0004435579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002445245,"about_ca_system_score_gemma":0.0001784169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003665504,"about_ca_topic_score_gemma":0.0005136237,"domain_scores_codex":[0.9998566,0.00001706076,0.00001845785,0.0000373789,0.0000470356,0.00002340484],"domain_scores_gemma":[0.9998165,0.00002280918,0.00008165182,0.0000238338,0.00001978546,0.00003551924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002383985,0.000002903507,0.0001250558,0.00001826171,0.000001179023,0.00003101594,0.000003743454,0.00001004976,0.999465,0.00002297785,0.000006838164,0.0002891308],"study_design_scores_gemma":[0.000003761373,0.00007284818,0.004830418,0.000005776899,0.000005753817,0.0002919413,0.00001354448,0.0002241679,0.9931743,0.00002756054,0.001346996,0.000002910062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912764,0.001319392,0.005614265,0.0001088735,0.0000325551,0.00002565369,0.0004840152,0.00009662598,0.001042339],"genre_scores_gemma":[0.992328,0.0005410581,0.005064732,0.00005695335,0.000006833368,0.00002267638,0.0006630662,0.00002655312,0.001290157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008883076,"threshold_uncertainty_score":0.002971709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005658864303109813,"score_gpt":0.2302534194709338,"score_spread":0.224594555167824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}