{"id":"W4386142014","doi":"10.3390/cancers15174229","title":"ARID1B Immunohistochemistry Is an Important Test for the Diagnosis of Dedifferentiated and Undifferentiated Gynecologic Malignancies","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"SMARCA4; SMARCB1; Immunohistochemistry; Targeted therapy; Medicine; Pathology; Biology; Cancer research; Oncology; Bioinformatics; Internal medicine; Cancer; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002023105,0.0004517367,0.000419348,0.002445752,0.0002947623,0.000515238,0.0003953264,0.0004647658,0.003572231],"category_scores_gemma":[0.002560503,0.0002860754,0.0003401221,0.0008000477,0.0004419842,0.0005421775,0.0004698237,0.0004639604,0.002091161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002989324,"about_ca_system_score_gemma":0.0002510934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007631592,"about_ca_topic_score_gemma":0.001330681,"domain_scores_codex":[0.9991384,0.0002190294,0.0001341073,0.0001156913,0.0003188004,0.00007394367],"domain_scores_gemma":[0.9990023,0.0003280206,0.0001561885,0.00007763781,0.000315749,0.0001201594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001220688,0.0001256624,0.4174396,0.001309076,0.0002330912,0.006463674,0.0003668355,0.0005603285,0.226718,0.001467385,0.01926338,0.3248323],"study_design_scores_gemma":[0.00009728327,0.00082061,0.5685177,0.00135385,0.0004181574,0.06735193,0.001003115,0.003095742,0.1240966,0.00312734,0.2299788,0.0001389809],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6626595,0.1868712,0.05371157,0.008917036,0.001904896,0.0005323356,0.005551277,0.00207129,0.077781],"genre_scores_gemma":[0.9061145,0.03783794,0.04058675,0.001206048,0.0006910636,0.0001805419,0.002917583,0.0001647968,0.01030063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003572231,"threshold_uncertainty_score":0.01195031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02370951453892914,"score_gpt":0.2834923017078441,"score_spread":0.2597827871689149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}