{"id":"W4386142014","doi":"10.3390/cancers15174229","title":"ARID1B Immunohistochemistry Is an Important Test for the Diagnosis of Dedifferentiated and Undifferentiated Gynecologic Malignancies","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"SMARCA4; SMARCB1; Immunohistochemistry; Targeted therapy; Medicine; Pathology; Biology; Cancer research; Oncology; Bioinformatics; Internal medicine; Cancer; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001048529,0.0001280306,0.0001435547,0.00002008467,0.0001172682,0.00001728438,0.0001623244,0.0001085048,0.00003716506],"category_scores_gemma":[0.0001358048,0.00009554392,0.00007566086,0.0001053825,0.0001325299,0.000002588032,0.00005577536,0.00004626911,6.134433e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006046605,"about_ca_system_score_gemma":0.0001753825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001173382,"about_ca_topic_score_gemma":0.00004270012,"domain_scores_codex":[0.9992468,0.00001031258,0.0002097077,0.0002559631,0.0000774597,0.0001997108],"domain_scores_gemma":[0.9993874,0.00007174441,0.0001220299,0.0002823809,0.00009091599,0.00004548067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000559863,0.00002050098,0.01806328,0.0001153234,0.0001327397,7.223645e-7,0.000185485,0.0002225661,0.9712388,0.000008436187,0.008088951,0.001867193],"study_design_scores_gemma":[0.001037475,0.0004122845,0.0305423,0.00005963352,0.0001543303,0.000004269575,0.0006649722,0.01059385,0.9531487,0.0002350183,0.002835106,0.0003120236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962392,0.002915605,0.0001304206,0.00008786801,0.000158263,0.000204537,0.0002138304,0.000025728,0.00002448869],"genre_scores_gemma":[0.9957861,0.003191948,0.00004712201,0.0001275837,0.00006720628,0.0002194448,0.0002254244,0.00001884075,0.000316298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01809007,"threshold_uncertainty_score":0.3896168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02370951453892914,"score_gpt":0.2834923017078441,"score_spread":0.2597827871689149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}