{"id":"W4386151486","doi":"10.1093/stmcls/sxad059","title":"Improved Cryopreservation of Human Induced Pluripotent Stem Cell (iPSC) and iPSC-derived Neurons Using Ice-Recrystallization Inhibitors","year":2023,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Cryopreservation; Biology; Cell biology; Cryoprotectant; Viability assay; Regenerative medicine; Cell; Stem cell; Embryonic stem cell; Embryo; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003355557,0.0002510532,0.0002608542,0.0002008136,0.0001826776,0.00005463881,0.0002526921,0.0002486176,0.00000842782],"category_scores_gemma":[0.00000838251,0.0002624289,0.0001006038,0.0004018643,0.00008408455,0.00002064992,0.0004165946,0.0001503403,0.000007978339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000387385,"about_ca_system_score_gemma":0.00009766322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001067425,"about_ca_topic_score_gemma":0.00003423997,"domain_scores_codex":[0.9979981,0.0002048719,0.0004911036,0.0005177166,0.0003510494,0.0004372151],"domain_scores_gemma":[0.9988739,0.00002935863,0.0002611564,0.0004791635,0.0002058348,0.0001505681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004490177,0.00005676583,0.0005917611,0.0002441796,0.00003054966,0.00000433493,0.000193283,0.0006522767,0.9973416,0.000003876644,0.0001999455,0.0006365732],"study_design_scores_gemma":[0.0007757777,0.0003537349,0.0007180541,0.00004525841,0.00002592664,0.000002241158,0.000663335,0.007126681,0.9896573,0.000007595868,0.0003781,0.0002460321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982837,0.000166183,0.000280233,0.00004491422,0.0002287653,0.0007073646,0.00003548822,0.00004368771,0.0002096097],"genre_scores_gemma":[0.9979829,0.00016622,0.00006140002,0.00002554816,0.0001185021,0.00002248933,0.0001281391,0.00006275086,0.001432095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007684289,"threshold_uncertainty_score":0.9999828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03762494358530069,"score_gpt":0.2724108159845489,"score_spread":0.2347858723992482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}