{"id":"W4386151486","doi":"10.1093/stmcls/sxad059","title":"Improved Cryopreservation of Human Induced Pluripotent Stem Cell (iPSC) and iPSC-derived Neurons Using Ice-Recrystallization Inhibitors","year":2023,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Cryopreservation; Biology; Cell biology; Cryoprotectant; Viability assay; Regenerative medicine; Cell; Stem cell; Embryonic stem cell; Embryo; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002455759,0.0004499343,0.0002244988,0.0001669061,0.000128569,0.0002746492,0.0002677599,0.0002090126,0.0007121864],"category_scores_gemma":[0.0002146924,0.0001040159,0.0002835233,0.0001090581,0.0001768881,0.0004239175,0.0002257887,0.000498813,0.000240145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002758732,"about_ca_system_score_gemma":0.0002438668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006438286,"about_ca_topic_score_gemma":0.001193176,"domain_scores_codex":[0.9998858,0.00001009767,0.00001695879,0.00003229639,0.00003709059,0.0000177697],"domain_scores_gemma":[0.9999083,0.00001840647,0.00003149857,0.00001038017,0.00002323928,0.000008177977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002818534,0.00001019406,0.000140183,0.00006992096,0.000008338716,0.00004795544,0.00002255511,0.0003728453,0.9963871,0.0001265608,0.00005840215,0.002727771],"study_design_scores_gemma":[0.000001866062,0.0000642501,0.0007375557,0.000008509275,0.00001398198,0.00006678393,0.000009235321,0.000634426,0.9966305,0.00002588132,0.001802847,0.000004113921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93408,0.01017175,0.04892067,0.0002466927,0.0001720454,0.0001746583,0.001123268,0.0003220912,0.00478886],"genre_scores_gemma":[0.965469,0.006061635,0.02183189,0.0001608624,0.00003237044,0.000154306,0.001449056,0.000116181,0.004724623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007121864,"threshold_uncertainty_score":0.002382517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03762494358530069,"score_gpt":0.2724108159845489,"score_spread":0.2347858723992482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}