{"id":"W4386152596","doi":"10.2196/46955","title":"Efficacy and Safety of the Smallpox Vaccine for Postexposure Prophylaxis in Monkeypox: Protocol for an Open-Labeled, Single-Armed Study","year":2023,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Health, Labour and Welfare","keywords":"Medicine; Monkeypox; Smallpox; Smallpox vaccine; Vaccinia; Vaccination; Virology; Adverse effect; Rash; Virus; Orthopoxvirus; Immunology; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0204626,0.004948859,0.006808283,0.001691025,0.003282689,0.002312853,0.002934677,0.006663573,0.03166333],"category_scores_gemma":[0.01467598,0.002030396,0.003655202,0.001605497,0.002702405,0.002991672,0.001711238,0.006610738,0.01014543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003585442,"about_ca_system_score_gemma":0.01319693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197931,"about_ca_topic_score_gemma":0.00204911,"domain_scores_codex":[0.9902771,0.004977991,0.001446611,0.0009964786,0.001106904,0.001194922],"domain_scores_gemma":[0.9890994,0.001628235,0.002385511,0.001574389,0.003530693,0.001781832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.7623256,0.09898317,0.005187698,0.01766282,0.001227305,0.0008333891,0.001241603,0.003943654,0.01356721,0.004627253,0.01956234,0.07083803],"study_design_scores_gemma":[0.4924749,0.3387647,0.01840172,0.005815235,0.001187865,0.0003839586,0.0005906736,0.003007774,0.006003185,0.003427938,0.129599,0.0003430647],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.006159334,0.0003388821,0.001297908,0.0001334198,0.0001624683,0.9894762,0.0009244452,0.00005640795,0.001450967],"genre_scores_gemma":[0.007353936,0.0003002651,0.002186855,0.0002867309,0.00009735332,0.988787,0.0003836185,0.000006969292,0.0005972362],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.03166333,"threshold_uncertainty_score":0.1082179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2960619483621462,"score_gpt":0.5282363579344952,"score_spread":0.232174409572349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}