{"id":"W4386154638","doi":"10.1038/s41583-023-00729-2","title":"Central regulation of stress-evoked peripheral immune responses","year":2023,"lang":"en","type":"review","venue":"Nature reviews. Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":171,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression; Canadian Institutes of Health Research; National Institute of Mental Health; Cure Alzheimer's Fund","keywords":"Immune system; Inflammation; Medicine; Neuroscience; Neutrophilia; Neuroimmunology; Sickness behavior; Immunology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003943524,0.00111523,0.001457156,0.001161295,0.0002273137,0.00117236,0.001112031,0.001403248,0.002750862],"category_scores_gemma":[0.0003572621,0.0002660052,0.0003909037,0.001135177,0.0006431157,0.001047138,0.0009028986,0.001848289,0.002137266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007953403,"about_ca_system_score_gemma":0.000991035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008734775,"about_ca_topic_score_gemma":0.001560877,"domain_scores_codex":[0.9998682,0.00002451247,0.00001574156,0.00002363784,0.0000476825,0.00002024101],"domain_scores_gemma":[0.9998589,0.00004807372,0.00003060071,0.00000570647,0.00003528097,0.00002140148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002213661,0.00006459568,0.0001611104,0.01693926,0.0001039226,0.0003861408,0.00004169521,0.0006360328,0.008613628,0.007120099,0.03734568,0.9283665],"study_design_scores_gemma":[0.00004636421,0.0001384755,0.001887252,0.004630401,0.000127211,0.001983964,0.00006341602,0.0002352078,0.001662795,0.006712755,0.9824821,0.00003007331],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008053279,0.9987072,0.0001303795,0.0002225737,0.0001764881,0.000003106615,0.00001517719,0.000005651502,0.0006589449],"genre_scores_gemma":[0.0005651265,0.9986252,0.00008816675,0.0001221051,0.0001815814,0.000005926616,0.00002152941,8.852398e-7,0.0003894959],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002750862,"threshold_uncertainty_score":0.0092026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08220558551661725,"score_gpt":0.3697038757985192,"score_spread":0.2874982902819019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}