{"id":"W4386191581","doi":"10.1002/ijc.34685","title":"Performance of the <scp>HPV E6</scp>/<scp>E7 mRNA</scp> Aptima <scp>HPV</scp> assay combined with partial genotyping compared with the <scp>HPV DNA</scp> Cobas 4800 <scp>HPV</scp> test for use in primary screening: Results from the <scp>CERVIVA HPV</scp> primary screening study in Ireland","year":2023,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Health Research Board","keywords":"Genotyping; Medicine; Cervical intraepithelial neoplasia; Cytology; Oncology; Cervical cancer; Gynecology; Internal medicine; Genotype; Biology; Cancer; Gene; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004799119,0.0009003596,0.0009684266,0.0009824693,0.0002185094,0.001015641,0.0006571236,0.0006537252,0.001231096],"category_scores_gemma":[0.007819403,0.0007347195,0.0009718159,0.0005359391,0.0006878839,0.0005004331,0.0007493626,0.0005657317,0.0008184068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001060863,"about_ca_system_score_gemma":0.0008200313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01350397,"about_ca_topic_score_gemma":0.01200525,"domain_scores_codex":[0.9937993,0.002324793,0.0004064927,0.001579964,0.00138131,0.0005081031],"domain_scores_gemma":[0.995185,0.001771709,0.0006352376,0.0004813304,0.001333024,0.0005937413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01924812,0.0006006832,0.8173953,0.0005603177,0.0005773005,0.0002653644,0.0006586986,0.001845262,0.07386433,0.00004744365,0.0008470975,0.08409013],"study_design_scores_gemma":[0.0002216986,0.01140346,0.9384001,0.00008278633,0.0005875867,0.001670583,0.0002612124,0.007294486,0.03863603,0.00005776233,0.001321118,0.00006317235],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965279,0.0005988716,0.0008021338,0.00007593498,0.00001859604,0.00005213209,0.0004277208,0.00004148294,0.001455253],"genre_scores_gemma":[0.9973249,0.0001428433,0.001318693,0.00004246281,0.00001228769,0.00002053931,0.0004926829,0.00001335935,0.0006321436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01350397,"threshold_uncertainty_score":0.02685076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04535397592545008,"score_gpt":0.3099439856622075,"score_spread":0.2645900097367574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}