{"id":"W4386222166","doi":"10.5713/ab.23.0210","title":"NANOG expression in parthenogenetic porcine blastocysts is required for intact lineage specification and pluripotency","year":2023,"lang":"en","type":"article","venue":"Animal Bioscience","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Research Foundation of Korea; Ministry of Trade, Industry and Energy; National Research Foundation","keywords":"Homeobox protein NANOG; Epiblast; Nanog Homeobox Protein; SOX2; Biology; Endoderm; Rex1; Homeobox; Embryo; Cell biology; Transcription factor; Molecular biology; Cellular differentiation; Embryonic stem cell; Embryogenesis; Genetics; Induced pluripotent stem cell; Gene; Gastrulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001832273,0.0003316835,0.000326186,0.0002857007,0.0001708119,0.0003175645,0.0002209225,0.0004402385,0.001976995],"category_scores_gemma":[0.0001890837,0.0002613931,0.0003003814,0.0001174248,0.0003785664,0.0002434688,0.0002629581,0.0004925883,0.0006447902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002664741,"about_ca_system_score_gemma":0.0002925609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005499822,"about_ca_topic_score_gemma":0.0006520362,"domain_scores_codex":[0.9998074,0.00002156804,0.00002215889,0.00004665477,0.0000671883,0.00003496614],"domain_scores_gemma":[0.9998457,0.00003550591,0.00004400808,0.00002153645,0.00001475101,0.00003838394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007032098,0.000008499508,0.0003584366,0.00003245678,0.00000239518,0.0001144241,0.00001404765,0.00002599493,0.9987292,0.00004549617,0.00001847417,0.0005801652],"study_design_scores_gemma":[0.0000396466,0.0003232427,0.02801425,0.00002650899,0.00003488056,0.0006973325,0.00008288348,0.0008125,0.9649653,0.00008179398,0.004915124,0.000006570974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882621,0.003128082,0.003603222,0.0001434172,0.00006610504,0.00006295521,0.0007329582,0.000111665,0.003889513],"genre_scores_gemma":[0.9849027,0.001464215,0.002360638,0.0001601028,0.00002383853,0.0001060138,0.002008368,0.00007253785,0.008901672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001976995,"threshold_uncertainty_score":0.006613731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03179702796174807,"score_gpt":0.3031006919362852,"score_spread":0.2713036639745371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}