{"id":"W4386222166","doi":"10.5713/ab.23.0210","title":"NANOG expression in parthenogenetic porcine blastocysts is required for intact lineage specification and pluripotency","year":2023,"lang":"en","type":"article","venue":"Animal Bioscience","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Research Foundation of Korea; Ministry of Trade, Industry and Energy; National Research Foundation","keywords":"Homeobox protein NANOG; Epiblast; Nanog Homeobox Protein; SOX2; Biology; Endoderm; Rex1; Homeobox; Embryo; Cell biology; Transcription factor; Molecular biology; Cellular differentiation; Embryonic stem cell; Embryogenesis; Genetics; Induced pluripotent stem cell; Gene; Gastrulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003983849,0.0001198369,0.0001087647,0.0001281253,0.00008919099,0.00003353112,0.0002501521,0.00009434815,0.000007153133],"category_scores_gemma":[0.0001450035,0.0001077932,0.00003665418,0.0003931256,0.0001322461,0.00001206148,0.0001936227,0.0000524474,0.00002698007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001416654,"about_ca_system_score_gemma":0.00005512607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008294479,"about_ca_topic_score_gemma":0.00001343643,"domain_scores_codex":[0.998621,0.00003767433,0.0002090042,0.0005694269,0.0001999123,0.0003629625],"domain_scores_gemma":[0.9994938,0.00002423436,0.0000594237,0.0002686617,0.00005950109,0.00009437287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001178502,0.00002624797,0.002831153,0.00002404325,0.0000016288,0.000003757545,0.00007794949,0.000004664122,0.9949772,0.00001219703,0.0010254,0.0008978741],"study_design_scores_gemma":[0.0004223548,0.0005418516,0.04155301,0.00003344921,0.000002066843,0.000005601991,0.00006713217,0.001562601,0.9493738,0.00003876908,0.006258665,0.0001406911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980322,0.0003644609,0.0004211882,0.0005021214,0.00005926838,0.0004184784,0.00003046026,0.00001719312,0.0001546222],"genre_scores_gemma":[0.997363,0.0007268515,0.0007112797,0.00009567721,0.00008153639,0.00005461979,0.00004521376,0.00001361978,0.000908174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04560342,"threshold_uncertainty_score":0.4395677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03179702796174807,"score_gpt":0.3031006919362852,"score_spread":0.2713036639745371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}