{"id":"W4386242003","doi":"10.1139/bcb-2023-0165","title":"Crosstalk between chromatin, chromosomes, and epigenetics","year":2023,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Epigenetics; Chromatin; Bivalent chromatin; Biology; Genetics; Crosstalk; Histone; Cancer epigenetics; Chromatin remodeling; Gene; Histone methyltransferase; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006852112,0.001117252,0.001210124,0.002517005,0.0005474467,0.001909666,0.0009952646,0.00174135,0.005599332],"category_scores_gemma":[0.0007221809,0.0002939687,0.0003523541,0.002707986,0.0009553537,0.00251827,0.001377798,0.00240309,0.00347351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001254533,"about_ca_system_score_gemma":0.001325481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00107636,"about_ca_topic_score_gemma":0.002207793,"domain_scores_codex":[0.9997979,0.00004330233,0.00002003849,0.00003838712,0.00007118176,0.0000292756],"domain_scores_gemma":[0.9997012,0.0001340275,0.00002716582,0.00001089229,0.00007768814,0.00004897827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006960832,0.00004985406,0.0001523012,0.00823693,0.00005280417,0.0003844298,0.0001025003,0.0002440362,0.001525957,0.0143909,0.08743138,0.8873593],"study_design_scores_gemma":[0.000006143843,0.00002230216,0.0002687171,0.001407859,0.0000218532,0.0009190388,0.00005680926,0.0000297765,0.0001859972,0.003774798,0.9932963,0.00001044439],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004088486,0.996991,0.0001014726,0.0006133686,0.0006077773,0.000002528505,0.000008651056,0.000008125233,0.001626138],"genre_scores_gemma":[0.0005624311,0.9970901,0.0001192266,0.0004422847,0.0005354874,0.000005108307,0.00001981248,0.00000168025,0.001223879],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005599332,"threshold_uncertainty_score":0.01873159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03408448177541214,"score_gpt":0.3199232730808741,"score_spread":0.285838791305462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}