{"id":"W4386243714","doi":"10.1016/s1470-2045(23)00344-3","title":"Tumor Treating Fields therapy with standard systemic therapy versus standard systemic therapy alone in metastatic non-small-cell lung cancer following progression on or after platinum-based therapy (LUNAR): a randomised, open-label, pivotal phase 3 study","year":2023,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Microbial Inactivation Methods","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"National Institutes of Health; Novocure","keywords":"Systemic therapy; Medicine; Lung cancer; Oncology; Cancer therapy; Cancer; Internal medicine; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001482242,0.001301036,0.003105041,0.0005412997,0.0003234294,0.001234524,0.0007533568,0.001515268,0.005742455],"category_scores_gemma":[0.0009969115,0.0005267308,0.002161456,0.0004724203,0.001324818,0.001239833,0.0004142474,0.003149091,0.0008275944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000982122,"about_ca_system_score_gemma":0.0008696976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027748,"about_ca_topic_score_gemma":0.002840243,"domain_scores_codex":[0.999512,0.0002376435,0.00001754354,0.0000921352,0.00003662247,0.0001041437],"domain_scores_gemma":[0.9993702,0.0002150718,0.0001249335,0.00005615611,0.00002872002,0.0002049989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9449683,0.01439051,0.0006636797,0.0005288165,0.0007241937,0.00002934816,0.00006214735,0.0008131763,0.004860185,0.0001467173,0.0008785835,0.03193431],"study_design_scores_gemma":[0.5636612,0.4281043,0.004042147,0.00006186782,0.0006108709,0.00005777002,0.00005933768,0.0009177267,0.001282428,0.0003213104,0.000855202,0.00002575131],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925835,0.003364193,0.0004288383,0.0003732797,0.0003689428,0.0009349278,0.0003971382,0.0000783143,0.001470804],"genre_scores_gemma":[0.9909399,0.002464673,0.0008997612,0.0005421655,0.0003217903,0.001025845,0.0005836867,0.00002888403,0.003193385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005742455,"threshold_uncertainty_score":0.01921046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07348996886503766,"score_gpt":0.4277260181715512,"score_spread":0.3542360493065135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}