{"id":"W4386245592","doi":"10.1111/joim.13709","title":"Precision cancer medicine: Concepts, current practice, and future developments","year":2023,"lang":"en","type":"review","venue":"Journal of Internal Medicine","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Current (fluid); Cancer; Medical physics; Precision medicine; Cancer Medicine; Intensive care medicine; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006314388,0.001046575,0.002046971,0.003139741,0.0005892102,0.003550447,0.001670533,0.00283349,0.003383671],"category_scores_gemma":[0.005693868,0.0004899699,0.001108867,0.003591751,0.002647948,0.004960247,0.001755136,0.005644247,0.001610964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002671285,"about_ca_system_score_gemma":0.004728544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001452162,"about_ca_topic_score_gemma":0.002559646,"domain_scores_codex":[0.9980988,0.000564359,0.0002422401,0.0002297816,0.0007161011,0.0001487032],"domain_scores_gemma":[0.9937,0.004326881,0.0003970238,0.0001881396,0.00105161,0.0003363487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008156624,0.00006844137,0.0002458609,0.02197289,0.0001127737,0.0002134454,0.0001769889,0.0006460736,0.000809184,0.02582803,0.0404099,0.909435],"study_design_scores_gemma":[0.00001739885,0.00008961058,0.0005166546,0.01168134,0.00008721321,0.000978312,0.0001761246,0.000202632,0.0002671357,0.01868596,0.9672598,0.00003788349],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004241146,0.9967109,0.0002645996,0.002121171,0.0003386598,0.000003675595,0.000008660063,0.000009134715,0.0005008513],"genre_scores_gemma":[0.0005692355,0.997512,0.0004336989,0.0008694858,0.0004351081,0.000007958832,0.00001436327,0.000002202965,0.0001559482],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006314388,"threshold_uncertainty_score":0.03339404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03592997335609398,"score_gpt":0.4263785319149448,"score_spread":0.3904485585588509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}