{"id":"W4386245592","doi":"10.1111/joim.13709","title":"Precision cancer medicine: Concepts, current practice, and future developments","year":2023,"lang":"en","type":"review","venue":"Journal of Internal Medicine","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Current (fluid); Cancer; Medical physics; Precision medicine; Cancer Medicine; Intensive care medicine; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000745792,0.0003354794,0.001194805,0.0002173553,0.00003807133,0.00001546226,0.0003683929,0.0002187277,0.00006330837],"category_scores_gemma":[0.001557711,0.0002030916,0.0001602297,0.000148061,0.0001545671,0.00000682574,0.0001828492,0.0005599504,0.000005233076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001078361,"about_ca_system_score_gemma":0.0005496403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003855453,"about_ca_topic_score_gemma":0.00001614488,"domain_scores_codex":[0.9978206,0.0001027174,0.001183744,0.0002697172,0.0004284871,0.0001947546],"domain_scores_gemma":[0.997192,0.0002798696,0.001620577,0.0001871018,0.0004844937,0.0002359472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008450563,0.00001947607,0.00002038635,0.001568154,0.0004284082,0.0000617547,0.00009493956,3.456317e-7,0.00002393543,0.00002077936,0.0982594,0.8994179],"study_design_scores_gemma":[0.0008337328,0.0007411606,0.00002711911,0.03149329,0.000848937,0.0007101648,0.0001372059,4.769964e-7,0.000007251737,0.00002235623,0.9650017,0.0001765923],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004594927,0.9913612,0.000138168,0.0008928195,0.006950569,0.000208632,0.00002743272,0.000002794137,0.0003724432],"genre_scores_gemma":[0.000008945349,0.9834665,0.0001594687,0.0004035381,0.01556889,0.00001249856,0.00003399069,0.00004812346,0.0002980349],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8992413,"threshold_uncertainty_score":0.8281836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03592997335609398,"score_gpt":0.4263785319149448,"score_spread":0.3904485585588509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}