{"id":"W4386246713","doi":"10.1101/2023.08.28.549404","title":"Structural and biophysical analysis of a <i>Haemophilus influenzae</i> tripartite ATP-independent periplasmic (TRAP) transporter","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Marsden Fund; Biomolecular Interaction Centre, University of Canterbury; Science for Life Laboratory; Umeå Universitet; Australian Cancer Research Foundation; Royal Society Te Apārangi; Knut och Alice Wallenbergs Stiftelse; Stockholms Universitet; Canterbury Medical Research Foundation; Kempestiftelserna; Australian Synchrotron; Kempe Foundation; Australian Nuclear Science and Technology Organisation; Australian Institute of Nuclear Science and Engineering","keywords":"Periplasmic space; Transporter; ATP-binding cassette transporter; Chemistry; Biophysics; Biochemistry; Biology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000822855,0.0001811768,0.00009708226,0.00006946114,0.0001688971,0.0001998047,0.0002268413,0.0002288606,0.0003455328],"category_scores_gemma":[0.0001391277,0.00009146146,0.0002024782,0.0001052512,0.0001307086,0.0001381032,0.000108061,0.000275497,0.0001578524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003523185,"about_ca_system_score_gemma":0.0001613817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00260053,"about_ca_topic_score_gemma":0.001728922,"domain_scores_codex":[0.9999605,0.000006260311,0.000002466375,0.000009037357,0.0000131172,0.00000858007],"domain_scores_gemma":[0.9999518,0.00000664895,0.00001197671,0.000004324583,0.00001212528,0.0000130743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008358684,0.00002214995,0.001139561,0.00003022281,0.000007943123,0.0001197187,0.00003927014,0.001024831,0.9966299,0.0001304211,0.00009784078,0.0006744666],"study_design_scores_gemma":[0.00004191896,0.0004030333,0.07459872,0.00001904086,0.00005533873,0.0008563166,0.0003200521,0.0480649,0.8700943,0.0003201524,0.005192278,0.00003389871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981999,0.0001655513,0.0009850196,0.00005925796,0.000004235131,0.000003530751,0.000169369,0.00001995273,0.0003930426],"genre_scores_gemma":[0.9966904,0.0001908965,0.00177888,0.00002638554,0.000002930667,0.000005594527,0.000888248,0.00001086935,0.0004058087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00260053,"threshold_uncertainty_score":0.005170822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01235198437907257,"score_gpt":0.2219190107307607,"score_spread":0.2095670263516881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}