{"id":"W4386251305","doi":"10.1111/epi.17744","title":"Can in vitro studies aid in the development and use of antiseizure therapies? A report of the ILAE/AES Joint Translational Task Force","year":2023,"lang":"en","type":"review","venue":"Epilepsia","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Agentura Pro Zdravotnický Výzkum České Republiky; Epilepsy Research UK; National Institute of Neurological Disorders and Stroke; Royal Society; Science Foundation Ireland; Savoy Foundation","keywords":"Neuroscience; Epilepsy; In vitro; Computer science; Medicine; Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002266908,0.0007628309,0.001267698,0.002477306,0.0002510154,0.001796616,0.001035835,0.001903152,0.003086706],"category_scores_gemma":[0.001737789,0.000337399,0.0006606539,0.001321453,0.0007931972,0.002618864,0.0007932289,0.002752204,0.003565176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007668143,"about_ca_system_score_gemma":0.001623357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001098962,"about_ca_topic_score_gemma":0.002312621,"domain_scores_codex":[0.9996011,0.0001019478,0.00005832389,0.00004941055,0.0001476787,0.00004164815],"domain_scores_gemma":[0.9990909,0.0004651923,0.000077844,0.00003347614,0.0002791404,0.00005339125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007783169,0.00009661114,0.0002034838,0.01579459,0.00005952205,0.0002828551,0.000101575,0.0003012002,0.007806206,0.01718214,0.05631647,0.9017776],"study_design_scores_gemma":[0.00001579574,0.00009655556,0.0004101543,0.00302787,0.00006616791,0.0007247439,0.00006267652,0.00006483089,0.001532736,0.002908763,0.9910707,0.00001890526],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001351633,0.9945508,0.0005116242,0.001284215,0.0007007818,0.00001457564,0.00003621892,0.00001445367,0.002752108],"genre_scores_gemma":[0.0006307947,0.9969108,0.0006939883,0.0006119565,0.0002684038,0.0000145068,0.00004381718,0.000004021735,0.0008218009],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003086706,"threshold_uncertainty_score":0.0119887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3026237654951831,"score_gpt":0.4271023609969086,"score_spread":0.1244785955017255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}