{"id":"W4386251314","doi":"10.1002/mc.23623","title":"JSI‐124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma","year":2023,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"Shandong University","keywords":"Autophagy; STAT3; STAT protein; Cancer research; Apoptosis; Biology; Cell growth; Programmed cell death; Bafilomycin; Activator (genetics); Cell biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001136386,0.000407014,0.0002259388,0.0004671793,0.0001616452,0.0001462573,0.0001802319,0.0002507578,0.0005645335],"category_scores_gemma":[0.00006627796,0.0001365447,0.0002937453,0.0001759112,0.0001934772,0.000141346,0.00009982726,0.00047255,0.0001558026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046932,"about_ca_system_score_gemma":0.0001711322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006275797,"about_ca_topic_score_gemma":0.0011106,"domain_scores_codex":[0.9999068,0.00001831799,0.00001242091,0.00001121051,0.00002609805,0.00002519591],"domain_scores_gemma":[0.9999385,0.000009148978,0.00001843172,0.000007382373,0.00000614823,0.00002027692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002856223,0.000168201,0.0002639796,0.00004283197,0.000008573036,0.00004076968,0.0000132159,0.0001291614,0.9976841,0.00005059334,0.0000609873,0.001251945],"study_design_scores_gemma":[0.00004811735,0.001191877,0.004635608,0.000005262064,0.00002142993,0.0001168771,0.00001742705,0.001204679,0.9917716,0.00002817919,0.0009555157,0.000003485496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964181,0.001370669,0.0006954261,0.00006938309,0.00002274397,0.00002323094,0.0002550107,0.00008628782,0.001059135],"genre_scores_gemma":[0.9962798,0.0010866,0.0008206403,0.00003029471,0.00001012842,0.00003283073,0.0003918791,0.00001035324,0.001337518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006275797,"threshold_uncertainty_score":0.001888573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006885613829024283,"score_gpt":0.2130613858944828,"score_spread":0.2061757720654585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}