{"id":"W4386270713","doi":"10.1016/s2152-2650(23)00549-9","title":"POSTER: CML-315 Assessment of Number Needed to Treat (NNT) and Cost per Response (CpR) in Patients (pts) With Relapsed/Refractory (R/R) Chronic Phase Chronic Myeloid Leukemia (CP-CML) Managed With Ponatinib (PON), Asciminib (ASC), and Bosutinib (BOS)","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"EVERSANA (Canada)","funders":"","keywords":"Medicine; Refractory (planetary science); Myeloid leukemia; Internal medicine; Number needed to treat; Intensive care medicine; Relative risk","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002354667,0.0002980647,0.0008988493,0.0003338245,0.0003042119,0.000894319,0.00041247,0.0006661329,0.02399142],"category_scores_gemma":[0.005969444,0.0001553074,0.002075942,0.0003212273,0.0002370987,0.0007830104,0.0005116867,0.001247913,0.002728421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001382281,"about_ca_system_score_gemma":0.0009230905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009895383,"about_ca_topic_score_gemma":0.001257124,"domain_scores_codex":[0.9992813,0.0003836312,0.00007088383,0.00007851081,0.000120339,0.00006534748],"domain_scores_gemma":[0.997451,0.000913888,0.0006067552,0.0001000027,0.0003133673,0.000615005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.2751462,0.005870804,0.1803754,0.003173438,0.005259113,0.0003049879,0.0002669316,0.01240565,0.002034499,0.002225021,0.09180222,0.4211358],"study_design_scores_gemma":[0.07077204,0.1249647,0.6646574,0.002989439,0.007025779,0.001328375,0.0009333823,0.04132539,0.004375547,0.009122971,0.07219213,0.0003129301],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9216655,0.006175786,0.002026214,0.01383575,0.001173205,0.002167274,0.02584858,0.0002116438,0.02689599],"genre_scores_gemma":[0.9790678,0.001375954,0.003321004,0.001813371,0.0004660331,0.001273685,0.005864451,0.00005079447,0.006766864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02399142,"threshold_uncertainty_score":0.08025926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02197721660446914,"score_gpt":0.3385809227854379,"score_spread":0.3166037061809688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}