{"id":"W4386270762","doi":"10.1016/s2152-2650(23)00862-5","title":"POSTER: MM-309 CARTITUDE-1 Final Results: Phase 1b/2 Study of Ciltacabtagene Autoleucel in Heavily Pretreated Patients With Relapsed/Refractory Multiple Myeloma","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Health Services; McGill University; Institute of Cancer Research; McGill University Health Centre; University of Calgary","funders":"","keywords":"Refractory (planetary science); Medicine; Multiple myeloma; Phase (matter); Phases of clinical research; Internal medicine; Nuclear medicine; Materials science; Chemistry; Clinical trial; Metallurgy; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001314303,0.001648715,0.001677111,0.0003722244,0.0006871239,0.00115785,0.0008385809,0.001608088,0.01285005],"category_scores_gemma":[0.0005651364,0.0004820732,0.001581346,0.0002219251,0.0006257998,0.0006460019,0.0004548411,0.003813603,0.002588853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001092012,"about_ca_system_score_gemma":0.001636111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002171691,"about_ca_topic_score_gemma":0.00528066,"domain_scores_codex":[0.9996487,0.0001269674,0.00001439291,0.00005124466,0.00003837492,0.0001202713],"domain_scores_gemma":[0.9995097,0.0000701785,0.00004594506,0.00002765893,0.0000292413,0.0003172535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4498114,0.0616678,0.006895874,0.001567817,0.00271087,0.0006745906,0.0004339886,0.00497291,0.07991031,0.00103431,0.1041394,0.2861808],"study_design_scores_gemma":[0.5476069,0.3820074,0.02472993,0.0001328587,0.0008573677,0.0004504549,0.00008565443,0.002166596,0.01061333,0.0005809661,0.03069111,0.00007748992],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9343677,0.009965156,0.002095187,0.00854413,0.00211709,0.007121711,0.01124156,0.00109587,0.02345164],"genre_scores_gemma":[0.936864,0.004860158,0.004124869,0.007003001,0.001108658,0.003239654,0.01009598,0.0003101057,0.03239359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01285005,"threshold_uncertainty_score":0.0429877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06028986609263801,"score_gpt":0.3668859926343511,"score_spread":0.306596126541713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}