{"id":"W4386270961","doi":"10.1016/s2152-2650(23)01076-5","title":"AML-521 The Randomized Phase III SIERRA (Study of Iomab-B in Elderly Relapsed or Refractory AML) Trial: Successful Allogeneic Hematopoietic Stem Cell Transplantation Using Treatment With Iomab-B-Led Regimen for Patients With Active, Relapsed or Refractory AML With Failed Targeted Therapies","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ottawa Hospital","funders":"","keywords":"Refractory (planetary science); Hematopoietic stem cell transplantation; Medicine; Regimen; Conditioning regimen; Internal medicine; Stem cell; Transplantation; Randomized controlled trial; Oncology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001237059,0.001396009,0.002107431,0.0003533897,0.0003305316,0.001510073,0.001040243,0.001014332,0.00546706],"category_scores_gemma":[0.001024099,0.0004424299,0.001669167,0.0003358177,0.0008478643,0.0007254775,0.0006529888,0.003316821,0.001288352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001138026,"about_ca_system_score_gemma":0.001365282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001582847,"about_ca_topic_score_gemma":0.00538807,"domain_scores_codex":[0.9996009,0.0002134712,0.00001455034,0.00006175241,0.00002596252,0.00008331794],"domain_scores_gemma":[0.9994593,0.00008801474,0.0001303954,0.00005853336,0.00002072592,0.0002430105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.898824,0.007807319,0.00357381,0.0008533225,0.002569893,0.0001184735,0.0001149833,0.001951305,0.01519241,0.00114542,0.01225121,0.05559778],"study_design_scores_gemma":[0.9416806,0.04475003,0.00549506,0.00004824425,0.001076718,0.0001609245,0.00003331497,0.0007062603,0.001355591,0.0003818777,0.004284419,0.00002689679],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9725276,0.007314087,0.001608672,0.002729042,0.0007068823,0.002537671,0.00530745,0.0004768139,0.006791758],"genre_scores_gemma":[0.9651524,0.005133879,0.003824448,0.003838587,0.0007188382,0.003600421,0.008772274,0.0001515392,0.008807562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00546706,"threshold_uncertainty_score":0.01828915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03855014632654694,"score_gpt":0.3425980365523169,"score_spread":0.3040478902257699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}