{"id":"W4386277530","doi":"10.1016/s2152-2650(23)00614-6","title":"POSTER: MDS-634 Efficacy and Safety of Oral Decitabine/Cedazuridine (ASTX727) in the CMML Subpopulation from Phase 2 and ASCERTAIN Phase 3 Studies","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Juravinski Cancer Centre; Sunnybrook Health Science Centre; Hôpital Maisonneuve-Rosemont; University of Alberta Hospital; Queen Elizabeth II Health Sciences Centre; Ottawa Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Decitabine; Phase (matter); Medicine; Internal medicine; Pharmacology; Chemistry; Biology; Genetics; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007840034,0.0006624344,0.0007721153,0.000249694,0.0004534573,0.0005400502,0.0004264273,0.000648597,0.01431314],"category_scores_gemma":[0.0005158465,0.000230381,0.0007976746,0.0001846586,0.0002804045,0.0002764392,0.0002811291,0.001751917,0.002089482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006735727,"about_ca_system_score_gemma":0.0009579869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001223553,"about_ca_topic_score_gemma":0.003455984,"domain_scores_codex":[0.9998078,0.00007362192,0.00001502535,0.00002418639,0.00003062991,0.00004873226],"domain_scores_gemma":[0.9997479,0.00005032405,0.00004316431,0.00001770914,0.00003634231,0.0001045409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.3647905,0.01259039,0.006419934,0.001384559,0.001210511,0.0004143526,0.0003565119,0.002227776,0.1636975,0.0007760224,0.06579019,0.3803418],"study_design_scores_gemma":[0.2459744,0.4359767,0.08879276,0.0003562026,0.002199656,0.001460499,0.000242195,0.002141587,0.1060333,0.00138823,0.115315,0.0001195639],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.950244,0.01299566,0.001406855,0.005693259,0.0008095851,0.001789217,0.007923277,0.0005105544,0.01862754],"genre_scores_gemma":[0.9523867,0.004991236,0.001962214,0.001735095,0.0004792736,0.0007901998,0.007279256,0.0001059836,0.03027001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01431314,"threshold_uncertainty_score":0.0478822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1073817430821689,"score_gpt":0.4665188563372431,"score_spread":0.3591371132550741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}