{"id":"W4386282232","doi":"10.1016/s2152-2650(23)00615-8","title":"POSTER: MDS-460 Efficacy of Pacritinib for Spleen, Symptoms, and Anemia Benefit in Myelofibrosis Patients Across the Cytopenic Spectrum","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Myelofibrosis; Ruxolitinib; Medicine; Anemia; Internal medicine; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003915499,0.0003614584,0.0006208612,0.0001834229,0.0002765998,0.0005454042,0.0002211271,0.0004402123,0.02435525],"category_scores_gemma":[0.000537525,0.0001143076,0.000712144,0.000114022,0.0001504908,0.000270975,0.0002290011,0.001586856,0.002185242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005047089,"about_ca_system_score_gemma":0.0005241343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006268531,"about_ca_topic_score_gemma":0.002185909,"domain_scores_codex":[0.9999025,0.00002821753,0.000007448973,0.00001487277,0.00001797679,0.00002898529],"domain_scores_gemma":[0.9998172,0.00003545235,0.00002810713,0.000006673094,0.00002247179,0.00009010276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1634661,0.004200468,0.009321909,0.00203494,0.001432815,0.0005624238,0.0001558313,0.001671994,0.0213803,0.002087758,0.1877435,0.6059419],"study_design_scores_gemma":[0.2141985,0.1343689,0.1834947,0.002443665,0.004574125,0.004625879,0.0003286513,0.004012429,0.02558992,0.004355016,0.4218234,0.0001848468],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7596087,0.06832063,0.001143884,0.02872322,0.006028928,0.001407427,0.01263659,0.0006147419,0.121516],"genre_scores_gemma":[0.9264628,0.01660196,0.001645309,0.01003723,0.003996145,0.0004751232,0.004875013,0.00007023135,0.03583622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02435525,"threshold_uncertainty_score":0.08147645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02847073835206524,"score_gpt":0.3454207431937757,"score_spread":0.3169500048417105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}