{"id":"W4386282346","doi":"10.1016/s2152-2650(23)00629-8","title":"POSTER: MPN-111 SVR (Spleen Volume Reduction) Predicts OS (Overall Survival) in MF (Myelofibrosis) Patients on PAC (Pacritinib) but Not BAT (Best Available Therapy): PERSIST-2 Landmark OS Analysis","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Myelofibrosis; Medicine; Spleen; Internal medicine; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001019151,0.0007137831,0.0007415964,0.0003598574,0.0003629646,0.001215857,0.0005743579,0.0005025209,0.008141141],"category_scores_gemma":[0.001364285,0.0002764796,0.001215566,0.0003667506,0.0002242718,0.0005809053,0.0006145575,0.001208854,0.001681499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006545674,"about_ca_system_score_gemma":0.0007555457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109654,"about_ca_topic_score_gemma":0.003904428,"domain_scores_codex":[0.9997748,0.00007451407,0.00001250592,0.00005817114,0.00004253108,0.00003752785],"domain_scores_gemma":[0.9991766,0.0001644488,0.000205228,0.00006848644,0.0001221477,0.0002631402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06795799,0.0009891832,0.7121794,0.000724343,0.003876157,0.0002017611,0.000157517,0.003442818,0.00776775,0.0005823621,0.05018147,0.1519392],"study_design_scores_gemma":[0.005305801,0.0099212,0.9488379,0.0002216688,0.005108591,0.0009087242,0.0002426582,0.005167607,0.004019222,0.001529709,0.01863138,0.0001054386],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612614,0.004694097,0.001054851,0.003163011,0.0003904359,0.0001887688,0.02033713,0.0001673046,0.008743014],"genre_scores_gemma":[0.9643088,0.001198409,0.002261484,0.000764354,0.0006536809,0.0002038414,0.02397017,0.00006750777,0.006571704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008141141,"threshold_uncertainty_score":0.02723479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04953592768175667,"score_gpt":0.3127973062949967,"score_spread":0.2632613786132401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}