{"id":"W4386317887","doi":"10.1093/dote/doad052.107","title":"268. DEVELOPMENT OF A NOVEL ESOPHAGUS-ON-A-CHIP MODEL: A HIGH-FIDELITY PLATFORM FOR DIRECTING PERSONALIZED THERAPY IN ESOPHAGEAL ADENOCARCINOMA","year":2023,"lang":"en","type":"article","venue":"Diseases of the Esophagus","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Chemotherapy; Esophagus; Docetaxel; Esophageal cancer; Pathology; Neoadjuvant therapy; Adenocarcinoma; Cancer research; Oncology; Internal medicine; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808037,0.0002553553,0.000177148,0.0001370932,0.0001350324,0.0003167366,0.0002780845,0.0004027378,0.001002415],"category_scores_gemma":[0.0001301423,0.0002190087,0.0003101811,0.00009034412,0.000162878,0.0001575086,0.0002158726,0.0002860367,0.0004691556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001946032,"about_ca_system_score_gemma":0.0002672837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008344992,"about_ca_topic_score_gemma":0.00137694,"domain_scores_codex":[0.9998848,0.00001127036,0.000008001171,0.0000330028,0.00004396298,0.0000188443],"domain_scores_gemma":[0.9999167,0.00001322111,0.00001823223,0.00001613332,0.00002035049,0.00001539564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002696377,0.00001911841,0.0003329653,0.00005613642,0.000005054403,0.00006427117,0.00001703338,0.001439522,0.9950207,0.0003123591,0.0001679319,0.002537984],"study_design_scores_gemma":[0.00001234401,0.0002427528,0.002437433,0.00001035457,0.00002262757,0.0002174186,0.00002795516,0.01836921,0.9707691,0.00009729563,0.007776869,0.00001662165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8355643,0.00126093,0.1534646,0.0002103132,0.0001654201,0.0002027989,0.002000725,0.0006693268,0.006461572],"genre_scores_gemma":[0.9154291,0.0008445604,0.07649195,0.00009571315,0.00001184822,0.0003253176,0.001453105,0.00007079603,0.005277473],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001002415,"threshold_uncertainty_score":0.003353357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06373962546171925,"score_gpt":0.3165465519529896,"score_spread":0.2528069264912703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}