{"id":"W4386330645","doi":"10.1101/2023.08.29.555372","title":"Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health; University of Minnesota","keywords":"Biology; Transcriptome; Gene knockdown; Wnt signaling pathway; Cell biology; Gene regulatory network; RNA-binding protein; CCR4; Translation (biology); Regulation of gene expression; Gene; Gene expression; Signal transduction; Messenger RNA; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009850482,0.0002644135,0.0002780119,0.0001839757,0.0001548524,0.0003578482,0.0001662788,0.0001576792,0.0006962638],"category_scores_gemma":[0.0001310197,0.0001582636,0.000257819,0.0001047131,0.0001608437,0.000187682,0.0002301823,0.0003364941,0.0002531482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004889526,"about_ca_system_score_gemma":0.000145804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007353853,"about_ca_topic_score_gemma":0.001044426,"domain_scores_codex":[0.9998841,0.00001106709,0.000006025134,0.00005020435,0.00003157799,0.00001690949],"domain_scores_gemma":[0.9999309,0.0000126713,0.00002604083,0.000006298913,0.00001130582,0.00001290688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008429722,0.000005852156,0.001905183,0.00004175105,0.0000086681,0.00003143646,0.00001215618,0.0005950097,0.9954785,0.00012837,0.00006134566,0.001647542],"study_design_scores_gemma":[0.00002321237,0.0001377266,0.05531568,0.00001783433,0.0000393733,0.0001099675,0.00009154373,0.02888068,0.9115981,0.0002264651,0.00353868,0.0000206794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901249,0.001256546,0.006442248,0.00005031902,0.00001613313,0.00001171747,0.0009935077,0.0001826092,0.0009218769],"genre_scores_gemma":[0.9953987,0.0002013022,0.002627811,0.00003943199,0.000003135168,0.00001442726,0.0009860127,0.00003620924,0.0006930867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007353853,"threshold_uncertainty_score":0.003547609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01541711438587414,"score_gpt":0.2328743920203636,"score_spread":0.2174572776344894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}