{"id":"W4386346833","doi":"10.1017/thg.2023.34","title":"Mitochondrial DNA Copy Number and Heteroplasmy in Monozygotic Twins Discordant for Schizophrenia","year":2023,"lang":"en","type":"article","venue":"Twin Research and Human Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Heteroplasmy; Mitochondrial DNA; Schizophrenia (object-oriented programming); Genetics; Biology; Medicine; Psychiatry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006073585,0.0001444836,0.0002098744,0.0001317877,0.000272635,0.00005677332,0.0001535752,0.0001449805,0.00001405111],"category_scores_gemma":[0.0001857669,0.0001397634,0.00004346311,0.0001603073,0.0002733845,0.000002848994,0.0002675198,0.0001635215,0.00001818898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001673486,"about_ca_system_score_gemma":0.00006378761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005348456,"about_ca_topic_score_gemma":0.0005591193,"domain_scores_codex":[0.9983521,0.0001605637,0.0002721038,0.000462821,0.0001498384,0.0006025602],"domain_scores_gemma":[0.9993213,0.0001195006,0.00004225091,0.000263228,0.00009925881,0.0001544273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005595721,0.000216532,0.56383,0.00015253,0.0001366095,0.00002147865,0.0004315339,0.0001642135,0.3951128,0.00182842,0.03413078,0.003415564],"study_design_scores_gemma":[0.008477163,0.003797394,0.8778213,0.00007563583,0.00003982659,0.00004489614,0.0009640194,0.002220854,0.02797637,0.03473508,0.0428897,0.0009578149],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983693,0.0003042569,0.0001767994,0.0002957928,0.0001048016,0.0004800097,0.00004745422,0.00001096878,0.0002106148],"genre_scores_gemma":[0.99463,0.0007938498,0.002273958,0.00004596189,0.0003634357,0.0001317788,0.0001667796,0.0000288627,0.001565324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3671364,"threshold_uncertainty_score":0.5699386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06230552958230033,"score_gpt":0.3836945027831634,"score_spread":0.321388973200863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}