{"id":"W4386350420","doi":"10.1016/j.hpb.2023.07.756","title":"Trial in Progress: Atezolizumab and Bevacizumab Pre-liver Transplantation for Patients with Hepatocellular Carcinoma beyond Milan Criteria","year":2023,"lang":"en","type":"article","venue":"HPB","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Milan criteria; Hepatocellular carcinoma; Bevacizumab; Atezolizumab; Liver transplantation; Internal medicine; Cirrhosis; Transplantation; Surgery; Oncology; Cancer; Gastroenterology; Chemotherapy; Nivolumab; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001384725,0.0002153531,0.0003309419,0.0002177431,0.00007983014,0.00003285325,0.00005048846,0.0001180381,0.00003768264],"category_scores_gemma":[0.00001462309,0.0001717951,0.00007554531,0.0002662885,0.00006325103,0.0001179243,0.00001428086,0.000082548,0.00001345252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005668745,"about_ca_system_score_gemma":0.00006372001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006565992,"about_ca_topic_score_gemma":0.00003217362,"domain_scores_codex":[0.9987086,0.00005428561,0.0002690688,0.0003794686,0.0002455197,0.0003430363],"domain_scores_gemma":[0.9994906,0.00006389757,0.00006048003,0.000179864,0.00008010546,0.0001250285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03713969,0.000295947,0.9477547,0.0005457329,0.00005210853,0.0004487886,0.001587204,7.772047e-8,0.00004970289,0.00001541042,0.0001884414,0.01192216],"study_design_scores_gemma":[0.1213363,0.004770135,0.855524,0.0001634818,0.0004471811,0.00002879106,0.00006274531,0.01566831,0.000876704,0.00003617517,0.000792686,0.0002934895],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952779,0.0004004854,0.00005274186,0.0001063256,0.00009984985,0.003792508,0.0001149155,0.00008567325,0.00006963834],"genre_scores_gemma":[0.9960639,0.0001113951,0.001204939,0.00003486879,0.00009341787,0.0007736799,0.001518451,0.00004337796,0.0001559864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09223074,"threshold_uncertainty_score":0.7005602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0345084265809307,"score_gpt":0.2631201585445158,"score_spread":0.2286117319635851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}