{"id":"W4386376231","doi":"10.1002/adfm.202306930","title":"Personalized Carbon Monoxide‐Loaded Biomimetic Single‐Atom Nanozyme for Ferroptosis‐Enhanced FLASH Radioimmunotherapy","year":2023,"lang":"en","type":"article","venue":"Advanced Functional Materials","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Youth Innovation Promotion Association of the Chinese Academy of Sciences; Youth Innovation Promotion Association; Chinese Academy of Sciences","keywords":"Cancer research; Radioimmunotherapy; Radiation therapy; Materials science; Glutathione; Cancer; Cancer cell; Chemistry; Biology; Medicine; Biochemistry; Immunology; Enzyme; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000640509,0.0002747194,0.0001767947,0.0001315182,0.00006393252,0.0001825629,0.000174528,0.0003894011,0.0005359003],"category_scores_gemma":[0.00008120015,0.0001093283,0.0001688252,0.00009346473,0.0001477621,0.0001649191,0.0001669153,0.000250735,0.0002068897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002592447,"about_ca_system_score_gemma":0.0001042718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002484962,"about_ca_topic_score_gemma":0.0003443246,"domain_scores_codex":[0.9999485,0.000004672416,0.000003233748,0.00001629465,0.00001523638,0.00001201158],"domain_scores_gemma":[0.9999541,0.000005319045,0.00001832522,0.000004935816,0.000008733351,0.000008602751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002157735,0.00001001094,0.00004810731,0.0000308135,0.000003613796,0.00002246149,0.000007499,0.0002247956,0.9978074,0.00007905992,0.00005492189,0.001689779],"study_design_scores_gemma":[0.000006052231,0.0000937908,0.0002812228,0.000001737738,0.000006069543,0.0000529051,0.000004378971,0.00208873,0.9961706,0.00001386677,0.001276849,0.000003862792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806198,0.001531297,0.01561999,0.0001322518,0.00006018144,0.00005249113,0.00008571268,0.0002225078,0.001675752],"genre_scores_gemma":[0.9910937,0.0004040288,0.006809826,0.00003986958,0.000007712149,0.00003031995,0.00004288131,0.00001510046,0.00155654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005359003,"threshold_uncertainty_score":0.001881003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01959523677400257,"score_gpt":0.2256108218730315,"score_spread":0.206015585099029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}