{"id":"W4386400773","doi":"10.1016/j.biopsych.2023.08.018","title":"Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Aging; National Institute of Mental Health; Helse Sør-Øst RHF; Instituto de Salud Carlos III; Horizon 2020; Sixth Framework Programme; Seventh Framework Programme; Horizon 2020 Framework Programme; Ministry of Cultural Affairs; National Institute of Biomedical Imaging and Bioengineering; Amsterdam Neuroscience; Fundación Marqués de Valdecilla; Heinz Nixdorf Stiftung; Ramsay Health Care; National Health and Medical Research Council; Neuraxpharm; H. Lundbeck A/S; Norges Idrettshøgskole; Medical Research Council; Epilepsy Society; Servier; Siemens Healthineers; Mission Interministérielle de Lutte Contre les Drogues et les Conduites Addictives; Fédération pour la Recherche sur le Cerveau; Australian Schizophrenia Research Bank; Ministero dell’Istruzione, dell’Università e della Ricerca; Norges Forskningsråd; Fondation de l'Avenir pour la Recherche Médicale Appliquée; Universitetet i Oslo; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Sanofi; Fondation de France; National Institute of Diabetes and Digestive and Kidney Diseases; King’s College London; Knut och Alice Wallenbergs Stiftelse; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institute on Drug Abuse; South London and Maudsley NHS Foundation Trust; Fondation pour la Recherche Médicale; Bundesministerium für Bildung und Forschung; National Institute of Child Health and Human Development; Hersenstichting; Radboud Universiteit; Ministero della Salute; Assistance Publique - Hôpitaux de Paris; Institut National de la Santé et de la Recherche Médicale; Universität Greifswald; Vistagen Therapeutics; Biogen; Agence Nationale de la Recherche; European Commission; European Research Council; King's College London; Pratt Foundation; National Institute for Health and Care Research; Cilag; Forschungszentrum Jülich; Pfizer; EU Joint Programme – Neurodegenerative Disease Research; Medical Research Foundation; Max Planck Instituut voor Psycholinguïstiek; Wellcome Trust; ZonMw; National Center for Research Resources; National Alliance for Research on Schizophrenia and Depression; Sunovion; Japan Society for the Promotion of Science; Avera Institute for Human Genetics; Astellas Pharma; Eisai; International Seafood Sustainability Foundation; U.S. Department of Energy; Australian Research Council; Fresenius Medical Care North America; Centre for Medical Systems Biology; Novo Nordisk; Sylvia and Charles Viertel Charitable Foundation; Waterloo Foundation; Science Foundation Ireland; National Institutes of Health; Stiftelsen Kristian Gerhard Jebsen; Baily Thomas Charitable Fund; European Science Foundation; Université Paris-Sud; Japan Agency for Medical Research and Development; Brain and Behavior Research Foundation","keywords":"Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004730379,0.0001872377,0.0001843238,0.0000224634,0.0001850415,0.00005274636,0.0002565469,0.0002486591,0.00003877495],"category_scores_gemma":[0.0001643195,0.0001149928,0.00007507785,0.000198435,0.0003300094,0.000004959868,0.000192883,0.0001298775,0.000006609142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002139716,"about_ca_system_score_gemma":0.00007811569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006995798,"about_ca_topic_score_gemma":0.0002670548,"domain_scores_codex":[0.9985811,0.0002727385,0.0002732743,0.0004391827,0.0001052727,0.0003284172],"domain_scores_gemma":[0.9995266,0.00007059185,0.00006902659,0.0002282959,0.00002224113,0.00008326711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004973351,0.00006247893,0.983826,0.00001215433,0.00003161256,9.064085e-7,0.0001174318,0.000002933396,0.0008638924,0.0134891,0.0007197366,0.0008240122],"study_design_scores_gemma":[0.0003387768,0.0002800135,0.9656112,0.000006123441,0.000008951212,0.000009487495,0.001204955,0.00004546561,0.00002894911,0.03144857,0.000831715,0.0001858],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949127,0.000252888,0.0002026404,0.002974561,0.0004635793,0.0001974338,0.0003020206,0.00003092152,0.0006632166],"genre_scores_gemma":[0.9985842,0.0001087009,0.0001619402,0.0005174757,0.0002787693,0.00004329488,0.0002404822,0.000005268388,0.00005989763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01821482,"threshold_uncertainty_score":0.468927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01662985915268351,"score_gpt":0.2396764766892785,"score_spread":0.223046617536595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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