{"id":"W4386418650","doi":"10.1016/j.lfs.2023.122063","title":"MitoQ combats tumor cell progression in Ehrlich ascites carcinoma mice: A crosstalk between mitochondrial oxidative status, mitophagy, and NF-κB signaling","year":2023,"lang":"en","type":"article","venue":"Life Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Mitophagy; Cancer research; PINK1; Biology; SOD2; Apoptosis; Superoxide dismutase; Oxidative stress; Biochemistry; Autophagy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002468186,0.0005367591,0.000367399,0.0004442143,0.0002172122,0.00030313,0.0002820021,0.0005101798,0.00195159],"category_scores_gemma":[0.0001425505,0.0001840971,0.0002713566,0.0001849892,0.0005042761,0.0004279024,0.0001961269,0.001194658,0.0002487703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000317952,"about_ca_system_score_gemma":0.0003950994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000716756,"about_ca_topic_score_gemma":0.00129451,"domain_scores_codex":[0.9998275,0.00002502342,0.0000136974,0.00003575004,0.00004313125,0.00005478831],"domain_scores_gemma":[0.9998403,0.00001325021,0.00004387374,0.00001864543,0.00001425916,0.00006965533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001014455,0.0001878546,0.0002393373,0.00004165457,0.00001061743,0.00006050841,0.00002144298,0.0001108204,0.9963145,0.0002736878,0.0001096626,0.001615596],"study_design_scores_gemma":[0.0002850241,0.003276009,0.006380169,0.00001964125,0.00005110498,0.0002695025,0.0001104197,0.001923024,0.984282,0.0004012041,0.002986349,0.00001547652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940399,0.001053917,0.002678286,0.0005574662,0.000100462,0.00003707685,0.0005005281,0.0001887248,0.0008436262],"genre_scores_gemma":[0.9949409,0.0007404197,0.001177883,0.00008934774,0.00002332983,0.00004116745,0.0002943807,0.00002123926,0.002671384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00195159,"threshold_uncertainty_score":0.006528676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02254831569217682,"score_gpt":0.3005571856742777,"score_spread":0.2780088699821009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}