{"id":"W4386418650","doi":"10.1016/j.lfs.2023.122063","title":"MitoQ combats tumor cell progression in Ehrlich ascites carcinoma mice: A crosstalk between mitochondrial oxidative status, mitophagy, and NF-κB signaling","year":2023,"lang":"en","type":"article","venue":"Life Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Mitophagy; Cancer research; PINK1; Biology; SOD2; Apoptosis; Superoxide dismutase; Oxidative stress; Biochemistry; Autophagy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003728044,0.0002054946,0.0002435193,0.0001975935,0.000309128,0.00009609393,0.0002549333,0.000154459,0.00002964123],"category_scores_gemma":[0.0003100373,0.0001751605,0.00006096543,0.0006352733,0.0004938868,0.00002081982,0.0002191267,0.0001485953,0.00003261188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001067632,"about_ca_system_score_gemma":0.000232024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008459402,"about_ca_topic_score_gemma":0.00005995253,"domain_scores_codex":[0.9979584,0.0002065409,0.0003153136,0.0007124711,0.0002703755,0.0005369472],"domain_scores_gemma":[0.9993225,0.0001196859,0.0001360436,0.0001773535,0.00006143394,0.000182976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007111042,0.00002872359,0.1830923,0.00002315299,0.000005964723,0.0000132196,0.0003826965,0.00003711618,0.813876,0.00001092864,0.002106949,0.0003517941],"study_design_scores_gemma":[0.001611855,0.0009497067,0.04025133,0.00005072761,0.00001510722,0.000009914342,0.001347515,0.0002438045,0.9447511,0.0001705537,0.01019382,0.000404534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969348,0.001117651,0.00008911454,0.0002033102,0.0008445767,0.0003451436,0.00005818967,0.00003235421,0.0003748258],"genre_scores_gemma":[0.9963236,0.00008549698,0.002071474,0.0002275124,0.000714456,0.00004103149,0.0001139004,0.00001452549,0.0004080007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.142841,"threshold_uncertainty_score":0.7142838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02254831569217682,"score_gpt":0.3005571856742777,"score_spread":0.2780088699821009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}