{"id":"W4386461582","doi":"10.3390/insects14090745","title":"Key Amino Acid Residues Involved in Binding Interactions between Bactrocera minax Odorant-Binding Protein 3 (BminOBP3) and Undecanol","year":2023,"lang":"en","type":"article","venue":"Insects","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Waterloo; National Natural Science Foundation of China","keywords":"Mutant; Odorant-binding protein; Biology; Alanine; Amino acid; Homology modeling; Binding site; Biochemistry; Ligand (biochemistry); Plasma protein binding; Docking (animal); Stereochemistry; Receptor; Chemistry; Enzyme; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003501337,0.0002342337,0.0003207955,0.0008897495,0.0004014914,0.00007693932,0.0003631154,0.0001720207,0.00005120157],"category_scores_gemma":[0.0007787819,0.0002251427,0.00005328843,0.0012704,0.000342909,0.0005232919,0.0003060237,0.0008198072,0.0003836365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000816427,"about_ca_system_score_gemma":0.00009748126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006585752,"about_ca_topic_score_gemma":0.0002155469,"domain_scores_codex":[0.9975288,0.0005134387,0.000327869,0.0007175776,0.000180009,0.0007322907],"domain_scores_gemma":[0.9985448,0.0009030839,0.0001021531,0.0002919796,0.00002903998,0.0001289806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008612296,0.00003600611,0.02286187,0.00005603641,0.000007932746,0.0001297893,0.0005047818,0.000001199193,0.9754088,0.0003051921,0.0002183164,0.0003839415],"study_design_scores_gemma":[0.0005509059,0.0002572609,0.04597605,0.0001356469,0.000005500735,0.00001759535,0.0001594046,0.00003516065,0.9515837,0.0006840045,0.0003733473,0.0002214521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975011,0.00001958035,0.000001708339,0.0004862106,0.0002077562,0.0005346355,0.00003501109,0.0001970035,0.00101693],"genre_scores_gemma":[0.9981866,0.00008503799,0.00002225962,0.0001323052,0.0001055714,0.0001105171,0.00003019483,0.00003333715,0.001294201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02382514,"threshold_uncertainty_score":0.9181051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08770028088996477,"score_gpt":0.3293097489568449,"score_spread":0.2416094680668801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}