{"id":"W4386465529","doi":"10.34133/research.0236","title":"Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression","year":2023,"lang":"en","type":"article","venue":"Research","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"CARE Canada; Toronto General Hospital; University of Toronto; Toronto Metropolitan University; Canadian Blood Services; St. Michael's Hospital","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Canadian Blood Services; Midwest Athletes Against Childhood Cancer","keywords":"Platelet; Immunology; Immune system; Platelet activation; Immunosuppression; Hemostasis; Medicine; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001005572,0.00007652931,0.0002173284,0.0002805626,0.00007775785,0.00001231134,0.0001707865,0.00009560191,0.00006871367],"category_scores_gemma":[0.00008850273,0.00004762418,0.00004985732,0.001043398,0.00005487655,0.00004025613,0.00006614431,0.0003102551,0.0002755525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000441618,"about_ca_system_score_gemma":0.00007917024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004598106,"about_ca_topic_score_gemma":0.000007846505,"domain_scores_codex":[0.9985336,0.000122561,0.0001846627,0.0001825204,0.0006357544,0.000340922],"domain_scores_gemma":[0.9993135,0.0002099075,0.00002897895,0.0003078129,0.0001022379,0.00003756477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004554867,0.002498814,0.004206865,0.001844255,0.0005012694,0.008209935,0.0297095,0.00004070904,0.9017531,0.005359576,0.01522187,0.02609926],"study_design_scores_gemma":[0.04855003,0.005302907,0.367951,0.01467884,0.000196636,0.003380198,0.02092727,0.07124411,0.4518495,0.008819358,0.00603659,0.001063544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968461,0.001183193,0.00001375234,0.0005438249,0.00002492321,0.0006537975,0.00001337484,0.00002320556,0.0006978338],"genre_scores_gemma":[0.9977894,0.001501951,0.00003093786,0.00004543745,0.00001299603,0.000046107,0.00001866205,0.00001417162,0.000540362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4499036,"threshold_uncertainty_score":0.3541762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1147561713736843,"score_gpt":0.3898391981998183,"score_spread":0.2750830268261341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}