{"id":"W4386465529","doi":"10.34133/research.0236","title":"Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression","year":2023,"lang":"en","type":"article","venue":"Research","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"CARE Canada; Toronto General Hospital; University of Toronto; Toronto Metropolitan University; Canadian Blood Services; St. Michael's Hospital","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Canadian Blood Services; Midwest Athletes Against Childhood Cancer","keywords":"Platelet; Immunology; Immune system; Platelet activation; Immunosuppression; Hemostasis; Medicine; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001859369,0.0002637242,0.0002125,0.0001596275,0.00008342847,0.0003901439,0.0001171321,0.0001835592,0.0008714474],"category_scores_gemma":[0.0001197561,0.00008215425,0.0001615729,0.0001031129,0.0001994072,0.000266473,0.0001808304,0.0004470198,0.0001517154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000168317,"about_ca_system_score_gemma":0.00009796553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009728724,"about_ca_topic_score_gemma":0.000111874,"domain_scores_codex":[0.9998792,0.00002918546,0.00000893757,0.0000265291,0.00003609854,0.00002001941],"domain_scores_gemma":[0.9999114,0.00001142062,0.00003940546,0.00001517087,0.000009421497,0.00001312174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002597722,0.00001567416,0.0006222325,0.00008115543,0.00001462039,0.0001863289,0.00002729026,0.0001100673,0.9884753,0.0006915014,0.0001143745,0.009401579],"study_design_scores_gemma":[0.00003399824,0.0007229957,0.01047731,0.00001922814,0.00005045237,0.001819935,0.00005782838,0.002149294,0.9737145,0.0007218145,0.01022242,0.00001006821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9624585,0.01442644,0.0197152,0.0004441384,0.00007291142,0.00003680836,0.0001354651,0.0002025503,0.002508049],"genre_scores_gemma":[0.9939529,0.002159422,0.001994049,0.000120677,0.00003618328,0.00002147363,0.00007703162,0.00001466363,0.001623696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008714474,"threshold_uncertainty_score":0.002915263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1147561713736843,"score_gpt":0.3898391981998183,"score_spread":0.2750830268261341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}