{"id":"W4386470455","doi":"10.1021/acsomega.3c04230","title":"Development of Gelled-Oil Nanoparticles for the Encapsulation and Release of Berberine","year":2023,"lang":"en","type":"article","venue":"ACS Omega","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology","funders":"National Research Council Canada","keywords":"Chemistry; Solubility; Nanocapsules; Berberine; Internalization; Nanoparticle; Chemical engineering; Organic chemistry; Materials science; Nanotechnology; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005082909,0.00007863293,0.000143292,0.00005153076,0.0001283192,0.000002455584,0.00009727437,0.00006887125,0.00001169502],"category_scores_gemma":[0.000110963,0.00006063451,0.00002588377,0.0001929902,0.0001021278,0.00005504759,0.0000628022,0.00007775884,0.000014796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001419128,"about_ca_system_score_gemma":0.00003811173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000461449,"about_ca_topic_score_gemma":0.00001295341,"domain_scores_codex":[0.9992651,0.00005660146,0.0003153581,0.000118233,0.0000859064,0.0001588051],"domain_scores_gemma":[0.9989479,0.00067367,0.0001399827,0.0001129498,0.00008088601,0.00004468102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002491254,0.00006645177,0.002040653,0.0002109061,0.0001409488,0.000001767432,0.003069998,0.00334953,0.8601156,0.001038974,0.0009379282,0.1287781],"study_design_scores_gemma":[0.001288732,0.0000454116,0.004563329,0.00002197157,0.00007291036,0.000003376362,0.0006851643,0.008362783,0.7830761,0.0002541663,0.2015131,0.0001128737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982691,0.0006471497,0.0001442652,0.0002820224,0.0002557946,0.0002136955,0.00002463267,0.00003181932,0.0001314708],"genre_scores_gemma":[0.997967,0.0002568494,0.0007696357,0.00006563143,0.00004158425,0.00007162267,0.00001232596,0.00001044523,0.0008049264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2005752,"threshold_uncertainty_score":0.2472604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1316359300315692,"score_gpt":0.4209014960246737,"score_spread":0.2892655659931045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}