{"id":"W4386471043","doi":"10.1016/j.pt.2023.08.006","title":"Hiding in plain sight: an epitope-based strategy for a subunit malaria vaccine","year":2023,"lang":"en","type":"review","venue":"Trends in Parasitology","topic":"Malaria Research and Control","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Health and Medical Research Council; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Epitope; Antigen; Immune system; Biology; Immunology; Virology; Malaria; Antigenic variation; Antibody; Protein subunit; Computational biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001088019,0.0005723229,0.003323367,0.002950757,0.00005762966,0.00003303133,0.0004586318,0.0009568254,0.0005950676],"category_scores_gemma":[0.000387664,0.0004767316,0.0004198222,0.001661171,0.00005813654,0.00006840892,0.00005428486,0.00121652,0.00008659982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002813295,"about_ca_system_score_gemma":0.000801726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003188568,"about_ca_topic_score_gemma":0.004921968,"domain_scores_codex":[0.9957512,0.0007812188,0.001172324,0.0008924782,0.0002578864,0.00114489],"domain_scores_gemma":[0.9974518,0.001193887,0.0002603578,0.0007191695,0.00006626429,0.0003084882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001105519,0.0004422905,0.001373008,0.008997758,0.0002801566,0.002515075,0.00003322908,0.00002946546,0.000004936351,0.00536597,0.0006417246,0.9792109],"study_design_scores_gemma":[0.0316506,0.006681353,0.01738581,0.01973124,0.002700369,0.0006518804,0.0001276471,0.008794493,0.00001260632,0.001453455,0.9087804,0.002030157],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003002788,0.9930872,0.0001482606,0.001849408,0.0004183791,0.002543087,0.0001774015,0.0001810191,0.001294948],"genre_scores_gemma":[0.008440621,0.979765,0.0004295031,0.0001235402,0.000853074,0.003541731,0.003526457,0.0002470055,0.003073082],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9771807,"threshold_uncertainty_score":0.9997684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1790134812171307,"score_gpt":0.4849029757996922,"score_spread":0.3058894945825614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}