{"id":"W4386475565","doi":"10.3390/antibiotics12091410","title":"Assessing the Activity under Different Physico-Chemical Conditions, Digestibility, and Innocuity of a GAPDH-Related Fish Antimicrobial Peptide and Analogs Thereof","year":2023,"lang":"en","type":"article","venue":"Antibiotics","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Université Laval","keywords":"Chemistry; Antimicrobial; Peptide; Divalent; Antimicrobial peptides; Biochemistry; Chromatography; Glyceraldehyde 3-phosphate dehydrogenase; Digestion (alchemy); Antibacterial activity; Biological activity; In vitro; Enzyme; Bacteria; Organic chemistry; Biology; Dehydrogenase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001762123,0.0002214241,0.0003956675,0.00007445495,0.000318093,0.00007703942,0.0001348024,0.0002299923,0.00003340416],"category_scores_gemma":[0.00006385715,0.0001599689,0.000088109,0.0002138836,0.001355728,0.0002048081,0.000291657,0.0003868562,0.00001517401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001826127,"about_ca_system_score_gemma":0.00003606982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001794312,"about_ca_topic_score_gemma":0.00003393381,"domain_scores_codex":[0.9988593,0.0001807707,0.0002655873,0.0003249587,0.00004383477,0.0003255506],"domain_scores_gemma":[0.9990079,0.0004726215,0.0001829902,0.0002586111,0.00005485243,0.00002299778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002382358,0.0001706257,0.02334289,0.00007122666,0.0001862312,0.000002627633,0.0002917392,0.000007029705,0.9711446,0.001003626,0.003171229,0.0005843127],"study_design_scores_gemma":[0.0007491905,0.00006456774,0.3980734,0.0001403471,0.0001284845,0.00005431322,0.0008760325,0.00006949234,0.5983599,0.00112759,0.0001116947,0.0002449662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981546,0.00005447548,0.00003855368,0.0008719828,0.0001959176,0.0001897154,0.0001608539,0.00007912322,0.00025482],"genre_scores_gemma":[0.9990699,0.0002082967,0.00001467921,0.0001708415,0.00002432604,3.028717e-7,0.0001303042,0.0000195168,0.0003618026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3747305,"threshold_uncertainty_score":0.6523343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02226313931953881,"score_gpt":0.286092879093746,"score_spread":0.2638297397742072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}