{"id":"W4386484621","doi":"10.1016/j.isci.2023.107843","title":"Promoting metabolic inefficiency for metabolic disease","year":2023,"lang":"en","type":"review","venue":"iScience","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Inefficiency; Metabolic disease; Chemistry; Biochemical engineering; Computational biology; Biology; Engineering; Economics; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005171002,0.0009616077,0.001107342,0.002304937,0.0003407258,0.00118126,0.0008724544,0.001284468,0.006908103],"category_scores_gemma":[0.0006834301,0.0002177601,0.0005087119,0.001666142,0.0006160355,0.001567334,0.001048047,0.002549714,0.004163303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000651059,"about_ca_system_score_gemma":0.000827723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005898429,"about_ca_topic_score_gemma":0.001406817,"domain_scores_codex":[0.999822,0.00003499083,0.00002207737,0.00002948682,0.00007117879,0.00002043404],"domain_scores_gemma":[0.9997731,0.0001032526,0.00003153789,0.00001119564,0.00005358661,0.0000273183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000755843,0.00007568774,0.0001080661,0.01328895,0.00009187321,0.0001961568,0.00005546434,0.0002419683,0.001647214,0.01009293,0.06190257,0.9122236],"study_design_scores_gemma":[0.00001348428,0.00003770791,0.0003235725,0.002565258,0.00004574822,0.0008486315,0.00002902946,0.00004750774,0.0002392853,0.003365974,0.9924731,0.00001076468],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005708383,0.9974064,0.0001578931,0.0003868456,0.000441671,0.000003849994,0.00001361003,0.00001118744,0.001521439],"genre_scores_gemma":[0.0005293872,0.9972411,0.0001863299,0.0004158923,0.0003208874,0.000006395834,0.00003337441,0.000002990708,0.001263541],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006908103,"threshold_uncertainty_score":0.02310985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1040505090878741,"score_gpt":0.4021727305996985,"score_spread":0.2981222215118244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}