{"id":"W4386496927","doi":"10.1128/spectrum.01256-23","title":"Analysis of SARS-CoV-2 isolates, namely the Wuhan strain, Delta variant, and Omicron variant, identifies differential immune profiles","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta; Government of Canada","keywords":"Immune system; Biology; Chemokine; Proinflammatory cytokine; Strain (injury); Pathogenesis; CD8; Galectin; Phenotype; Immunology; T cell; Virology; Inflammation; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006119781,0.0003229165,0.0008896122,0.0008216266,0.0002304803,0.00006756852,0.0004268514,0.0002928922,0.00006451782],"category_scores_gemma":[0.00009169629,0.0002268098,0.0003380624,0.001480052,0.0007141334,0.0000645392,0.0003809326,0.0004634861,0.00007970585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006427406,"about_ca_system_score_gemma":0.0001625555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001274399,"about_ca_topic_score_gemma":0.0009407119,"domain_scores_codex":[0.9976689,0.0002311882,0.0006097829,0.0006430158,0.0001167443,0.0007304033],"domain_scores_gemma":[0.9987308,0.0002531704,0.0002031056,0.0006932477,0.00009209691,0.00002761762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003684626,0.0001232982,0.00903115,0.00009701903,0.002567053,0.0001207675,0.0005710205,4.570318e-7,0.9855968,0.0004243709,0.0007800367,0.000319508],"study_design_scores_gemma":[0.001579969,0.0003865568,0.0747545,0.00006139551,0.001618839,0.0002965462,0.0003837351,0.0008856334,0.9137353,0.0004766616,0.005518171,0.0003027394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952424,0.001135722,0.0002450533,0.001892142,0.0002302187,0.000546922,0.0004168021,0.0001168098,0.0001739452],"genre_scores_gemma":[0.9969391,0.0000825582,0.00003802971,0.002331461,0.0001181094,0.00002982029,0.0002763376,0.00003808574,0.0001465191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0718616,"threshold_uncertainty_score":0.9249035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02796419100847488,"score_gpt":0.3085445726545809,"score_spread":0.280580381646106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}