{"id":"W4386529334","doi":"10.1002/1878-0261.13519","title":"Transcriptomic profiling of peripheral blood cells in <scp>HPV</scp> ‐associated carcinoma patients receiving combined valproic acid and avelumab","year":2023,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta; Alberta Cancer Foundation; Institute of Infection and Immunity; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Avelumab; Peripheral blood mononuclear cell; Immune system; Immunology; Cancer research; Immunotherapy; Transcriptome; Chemokine; Medicine; Ipilimumab; Biology; Nivolumab; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004670883,0.0002658018,0.0006569157,0.0002833383,0.00009521425,0.000008408122,0.0002806989,0.0006053747,0.0000532634],"category_scores_gemma":[0.0002813973,0.0002927892,0.000117719,0.0004634573,0.0002878631,0.00005471615,0.0001497796,0.0005329468,0.00004679697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002172198,"about_ca_system_score_gemma":0.0001988071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000974951,"about_ca_topic_score_gemma":0.00007969791,"domain_scores_codex":[0.9975421,0.0006437875,0.0005889023,0.0004762018,0.00006686086,0.0006821937],"domain_scores_gemma":[0.9990923,0.0002395631,0.0002444541,0.0002809096,0.0001133984,0.00002934349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007187631,0.0003807098,0.04185564,0.00006655281,0.0001917631,0.0000665775,0.002334321,0.00002987022,0.9532504,0.00003971736,0.0002832221,0.001429348],"study_design_scores_gemma":[0.008304533,0.001069759,0.08836826,0.00003991003,0.0001078822,0.00001179617,0.000512098,0.00005399822,0.9007386,0.00008749292,0.0005740036,0.000131643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953465,0.001590847,0.00002243952,0.00006205557,0.001249587,0.0006156189,0.00003423774,0.00008505482,0.0009936151],"genre_scores_gemma":[0.9987165,0.0001157919,0.0001467976,0.0001464828,0.000007652612,0.00008216152,0.0002128587,0.00005169293,0.00052002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05251177,"threshold_uncertainty_score":0.9999524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00828183992090572,"score_gpt":0.2266473448362278,"score_spread":0.2183655049153221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}