{"id":"W4386529783","doi":"10.1007/s40257-023-00806-3","title":"Tralokinumab Efficacy Over 1 Year in Adults with Moderate-to-Severe Atopic Dermatitis: Pooled Data from Two Phase III Trials","year":2023,"lang":"en","type":"article","venue":"American Journal of Clinical Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Queen's University","funders":"LEO Pharma; Ludwig-Maximilians-Universität München","keywords":"Medicine; Eczema Area and Severity Index; Placebo; Post-hoc analysis; Atopic dermatitis; Regimen; Randomized controlled trial; Internal medicine; Clinical trial; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0150828,0.001579384,0.006730888,0.0008938978,0.0004453687,0.001833411,0.0008135778,0.001489475,0.001613597],"category_scores_gemma":[0.008378805,0.0006993494,0.01134503,0.001508362,0.0003975298,0.00121654,0.0005968784,0.002172835,0.0002545534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008200727,"about_ca_system_score_gemma":0.001187208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001056554,"about_ca_topic_score_gemma":0.003445308,"domain_scores_codex":[0.9957368,0.001925221,0.0007849891,0.000735782,0.0005439969,0.0002732035],"domain_scores_gemma":[0.9940822,0.00230291,0.002215234,0.0004296648,0.0005547972,0.0004152963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5008708,0.001352723,0.03284938,0.02620487,0.2841617,0.0002363146,0.000277342,0.002407461,0.008607645,0.0001712036,0.005610229,0.1372504],"study_design_scores_gemma":[0.2164319,0.08458729,0.2473591,0.003204189,0.4309166,0.0009691273,0.000181356,0.001532175,0.002998173,0.000534419,0.01109514,0.0001905318],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4799515,0.5052772,0.002399566,0.0010444,0.0007136926,0.001751167,0.005203259,0.0002723677,0.003386855],"genre_scores_gemma":[0.9174591,0.07112078,0.001699493,0.001646649,0.0007083653,0.001350182,0.005051099,0.00004814631,0.0009160296],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0150828,"threshold_uncertainty_score":0.07976645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07569444120710184,"score_gpt":0.4378672501877615,"score_spread":0.3621728089806596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}