{"id":"W4386537608","doi":"10.1093/neuonc/noad137.101","title":"P02.16.B COMPENSATORY CROSS-TALK BETWEEN AUTOPHAGY AND GLYCOLYSIS REGULATES SENESCENCE AND STEMNESS IN HETEROGENEOUS GLIOBLASTOMA TUMOR SUBPOPULATIONS","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Manitoba","funders":"","keywords":"Biology; Glycolysis; Cancer research; Autophagy; Stem cell; Senescence; Cancer stem cell; Downregulation and upregulation; Cell biology; Apoptosis; Biochemistry; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002765399,0.0002750962,0.0002952525,0.0005481823,0.0003711816,0.0007930797,0.0002159286,0.0003731877,0.009460093],"category_scores_gemma":[0.0002077299,0.0001556354,0.0002266547,0.0004631472,0.0003262037,0.0002214837,0.0003086295,0.0005634441,0.00299784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000293405,"about_ca_system_score_gemma":0.0004888936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005087548,"about_ca_topic_score_gemma":0.0004447486,"domain_scores_codex":[0.9998385,0.00001858667,0.0000131142,0.00004935785,0.00004094509,0.00003940367],"domain_scores_gemma":[0.9997856,0.00002126927,0.00007245092,0.00002186156,0.0000306801,0.00006817411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009411245,0.0001010363,0.005284831,0.0001603028,0.00002498239,0.0004844286,0.00009756722,0.0001523193,0.9796425,0.001421215,0.001380879,0.01030881],"study_design_scores_gemma":[0.0002368158,0.0011024,0.1478318,0.00008469033,0.0001125051,0.006696919,0.0005732536,0.007514047,0.7767118,0.002237608,0.05685854,0.00003958499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682655,0.001758256,0.01170233,0.0004894062,0.0001937611,0.0001121655,0.009114607,0.001055575,0.007308439],"genre_scores_gemma":[0.983745,0.0005856446,0.002716288,0.0001279065,0.00002724268,0.0001393306,0.004869577,0.0001934156,0.007595718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009460093,"threshold_uncertainty_score":0.03164715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484539402643402,"score_gpt":0.2903988259796543,"score_spread":0.2755534319532202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}