{"id":"W4386537623","doi":"10.1093/neuonc/noad137.220","title":"P10.22.B COMBINATION OF ARTS MIMETICS WITH AUTOPHAGY INHIBITORS AS A NOVEL THERAPEUTIC STRATEGY TO OVERCOME APOPTOSIS RESISTANCE IN GLIOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Manitoba","funders":"Institut National Du Cancer; European Commission","keywords":"Apoptosis; Autophagy; Programmed cell death; In vivo; Cancer research; Medicine; Downregulation and upregulation; Radiation therapy; Chemistry; Biology; Internal medicine; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009320013,0.0003451619,0.0003267014,0.0002803769,0.0001166959,0.0002359207,0.0002131565,0.0002741264,0.001758213],"category_scores_gemma":[0.00005699725,0.00009567795,0.0002291575,0.0001322817,0.0001588683,0.0001572136,0.0001313038,0.0004662472,0.0005005918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001933307,"about_ca_system_score_gemma":0.0002274767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003868704,"about_ca_topic_score_gemma":0.0004959033,"domain_scores_codex":[0.9999423,0.000007272919,0.00000571456,0.00001180498,0.00001556761,0.0000172458],"domain_scores_gemma":[0.9999715,0.000003293047,0.000006191623,0.000002756899,0.00000460441,0.0000116407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005487649,0.0002921379,0.0001495228,0.0001476293,0.00001794641,0.0001808212,0.00001305256,0.0004170404,0.9854304,0.0002639999,0.0005045169,0.01203421],"study_design_scores_gemma":[0.000142718,0.003689453,0.001534076,0.00001775835,0.00005106122,0.0005479958,0.00002080633,0.002216214,0.9807772,0.0000993194,0.01089081,0.0000125722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818842,0.006275527,0.004429714,0.000364242,0.0002496365,0.0002099556,0.0006461083,0.0002814316,0.005659127],"genre_scores_gemma":[0.9866384,0.003145161,0.004204595,0.0001683869,0.0000468195,0.0001575663,0.0007428894,0.0000333529,0.004862774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001758213,"threshold_uncertainty_score":0.005881846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672127724764821,"score_gpt":0.2619205941235698,"score_spread":0.2451993168759216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}