{"id":"W4386540934","doi":"10.1016/j.medj.2023.06.005","title":"Translational roadmap for regenerative therapies of eye disease","year":2023,"lang":"no","type":"article","venue":"Med","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Eye Institute; Genentech; Santen","keywords":"Regenerative medicine; Neuroscience; Clinical trial; Medicine; Disease; Population; Biology; Pathology; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00507838,0.001094362,0.001612013,0.00143323,0.0009451602,0.004741157,0.001759152,0.004067466,0.04252528],"category_scores_gemma":[0.002888831,0.0003536978,0.0009932508,0.0008754728,0.001909754,0.003850823,0.002272339,0.005782442,0.008593131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002067832,"about_ca_system_score_gemma":0.007886872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001153763,"about_ca_topic_score_gemma":0.002067661,"domain_scores_codex":[0.9989836,0.0003330796,0.00007734889,0.000100845,0.0001735681,0.0003315716],"domain_scores_gemma":[0.9963826,0.00134412,0.0002699271,0.000218548,0.000924864,0.0008598734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002339319,0.002119293,0.00195549,0.005890627,0.000226458,0.001231771,0.0003008164,0.001779014,0.03714618,0.1641682,0.1654493,0.6173934],"study_design_scores_gemma":[0.0005920454,0.003481641,0.003621599,0.002661695,0.0002818074,0.001131371,0.0009588593,0.002116649,0.01141237,0.124945,0.8487157,0.00008116043],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01652632,0.688162,0.02834078,0.1762716,0.009551313,0.0005790269,0.002949384,0.001648455,0.07597106],"genre_scores_gemma":[0.162851,0.6968367,0.0472983,0.04633109,0.01259537,0.001443407,0.007870619,0.0002981161,0.02447543],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.04252528,"threshold_uncertainty_score":0.1422613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704983177643643,"score_gpt":0.2864377980735188,"score_spread":0.2693879662970824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}